Apical sparing in tako‐tsubo cardiomyopathy

Abdulla, Irfan; Kay, Sharon; Mussap, C.; Nelson, G.; Rasmussen, Helge H.; Hansen, Peter S.; Ward, Michael R.

doi:10.1111/j.1445-5994.2006.01095.x

Cited by 63 publications

(63 citation statements)

References 8 publications

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“…The syndrome was first described in the Japanese population in 1991 and was given the name 'Tako-Tsubo' after the round bottomed and narrow necked Japanese fishing pot that resembles the characteristic shape of the left ventricle during systole in this condition [3]. Since then there have been several case series from North America [4,5,6,7,8], Europe [9,10,11], Asia [12,13,14] and Australia [15]. TTC has been recognized as a primary acquired cardiomyopathy in the American Heart Association scientific statement on the classification of cardiomyopathies [16].…”

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confidence: 99%

Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis

Madhavan

Prasad

2010

Herz

247

160

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Tako-Tsubo cardiomyopathy (TTC) is a reversible cardiomyopathy with a clinical presentation indistinguishable from myocardial infarction. TTC is estimated to represent 1%-2% of patients presenting with acute myocardial infarction. It most commonly occurs in postmenopausal women and is frequently precipitated by a stressful event. Chest pain and dyspnea are the typical presenting symptoms. Transient ST-segment elevation on ECG and a small rise in cardiac biomarkers are common. Characteristic wall motion abnormalities extend beyond the territory of a single epicardial coronary artery in the absence of obstructive coronary lesions. Supportive treatment leads to spontaneous rapid recovery in nearly all patients. The prognosis is excellent, and recurrence occurs in < 10% of patients. In this article, we review the clinical features of TTC that form the basis of the Mayo Clinic diagnostic criteria, as well as the long-term prognosis for this type of cardiomyopathy.

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mentioning

confidence: 99%

Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis

Madhavan

Prasad

2010

Herz

247

160

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“…Therefore, the state of oestrogen deficiency in the post-menopausal period may act to pre-dispose woman to Tako-tsubo syndrome, by removing an important means to modulate sympathetic outflow and microcirculatory resistance. The suggestion that oestrogen desensitises the heart to catecholamines and then creates a state of rebound hypersensitivity in post-menopausal women, is not supported by findings of Abdulla et al in a study showing the occurrence of Tako-tsubo syndrome in pre-menopausal women [43]. Whilst oestrogen deficiency may play a contributory role, it is unlikely to represent a mechanism for Tako-tsubo syndrome in its own right.…”

Section: Catecholaminesmentioning

confidence: 92%

Management of Tako-tsubo Syndrome

Tarkin

Khetyar

Kaski

2007

Cardiovasc Drugs Ther

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“…Jüngst wurde auch eine neue Variante des TTS mit Aussparung der Herzspitze beschrieben (Abbildung 2). Die Klinik und der zeitlicher Verlauf sind ähnlich wie bei der klassischen Form von Takotsubo [44].…”

Section: Klinikunclassified

“…Da diese Befunde unspezifisch sind, spielt die Myokardbiopsie beim typischen Bild eines TTS weder für die Diagnose noch für die Therapie eine Rolle [44,46].…”

Section: Imunclassified

Das Takotsubo-Syndrom von der Erstbeschreibung bis heute

et al. 2009

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Stress-induced cardiomyopathy, also known as takotsubo syndrome, imitates an acute ST elevation myocardial infarction or an acute coronary syndrome, but without concomitant coronary artery disease. It mainly affects postmenopausal women, but no established epidemiologic data of this syndrome are available to date. Furthermore, the underlying etiologies are still largely unknown. The most frequently described trigger is strong emotional stress. Supportive therapy with aspirin, beta-blockers and angiotensin-converting enzyme inhibitors is recommended. The abnormal kinetics usually reverse or improve within 4-5 weeks. Compared with acute myocardial infarction, takotsubo cardiomyopathy carries a favorable prognosis. However, severe complications, including ventricular fibrillation and cardiogenic shock, may still occur.

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Apical sparing in tako‐tsubo cardiomyopathy

Abstract: The apical sparing variant of TTC is common, accounting for 40% of cases. While the patients are younger and more likely premenopausal, there are no other distinguishing features between the classical and the variant form.

Cited by 63 publications

References 8 publications

Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis

Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis

Management of Tako-tsubo Syndrome

Das Takotsubo-Syndrom von der Erstbeschreibung bis heute

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