Apocrine Adenocarcinoma of Lacrimal Sac Presenting as Chronic Dacryocystitis

Hoang, Amber

doi:10.24966/ocr-8887/100027

Cited by 3 publications

(4 citation statements)

References 10 publications

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“…Local orbital and periorbital invasion was described in 47% of the patients [10]. In a case reported by Hoang et al, apocrine adenocarcinoma in the lacrimal sac presented as a masquerading chronic dacryocystitis [11]. In another case reported by Shintaku et al, the neoplasm was located in the subcutaneous tissue of the eyelid in the medial canthus and showed a subconjunctival spread in the lacrimal caruncle [12].…”

Section: Discussionmentioning

confidence: 98%

Primary apocrine adenocarcinoma of the orbit with lacrimal sac invasion

et al. 2020

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Section: Discussionmentioning

confidence: 98%

Primary apocrine adenocarcinoma of the orbit with lacrimal sac invasion

et al. 2020

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“…To date 27 cases of OAAA arising in eyelids, two cases originating from the lacrimal caruncle and one case from the lacrimal sac have been described in the literature (Table 1) (ref. 1,[3][4][5][6][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] ).…”

Section: Discussionmentioning

confidence: 99%

“…Ocular adnexal apocrine adenocarcinoma (OAAA) is an extremely rare tumor emerging from modified apocrine glands of the eyelids (glands of Moll), which are situated at the base of eyelash follicles. A quite unique origin of OAAA from sweat glands of the lacrimal caruncle or lacrimal sac was also described 1,3,4 . OAAA was first reported by Stout and Cooley in 1951 (ref.…”

Section: Introductionmentioning

confidence: 91%

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Cervical lymphocele: A rare complication following salvage surgery for ocular adnexal apocrine adenocarcinoma. A case report and review of the literature

et al. 2022

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Background. An ocular adnexal apocrine adenocarcinoma (OAAA) is an extremely rare, but potentially aggressive and life-threatening tumor with ill-defined management based only on recommendations from a limited number of reported cases. The development of cervical lymphocele following neck dissection is a very rare complication, but one with well established methods for prevention and treatment. Here we describe a previously unreported case of salvage surgery including neck dissection for OAAA in addition to an emergence of cervical lymphocele. A literature review of current knowledge on both pathological conditions is included. Methods and Results. A 58-year-old man suffering from OAAA, previously treated with multiple eye-sparing excisions and adjuvant proton therapy, underwent salvage surgery for locoregional recurrence of the tumor. A partial orbitectomy with orbital exenteration, primary reconstruction and left-sided neck dissection was performed. The procedure was complicated by a cervical lymphocele resolved after the surgical therapy. The patient remained disease-free during the one-year follow-up. Conclusion.OAAA is a locally aggressive tumor with potential to local or distant metastatic spread. Whole-body staging, regular clinico-radiological follow-up and stage-dependent therapy with surgery as the first-choice treatment is required. A cervical lymphocele as a complication of especially left-sided neck dissection is managed with a conservative or surgical therapy according to the level of lymph leakage, extent and localization of lesions, presence of local or systemic disorders and the period from primary surgery.

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A case of an apocrine adenocarcinoma originating in the eyelid

Sakamoto,

Hirose,

Takemoto

et al. 2024

Toukeibu geka

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Apocrine adenocarcinoma is a rare tumor that originates from the apocrine gland. Most of them are reported to occur in the axilla ; apocrine adenocarcinoma arising from the eyelid is extremely rare. We experienced a case of apocrine adenocarcinoma that arose from the lower right eyelid. The case was a man in his 70s who visited an ophthalmologist with a chief complaint of right lacrimation. The ophthalmologist found him to have a right orbital tumor by using enhanced MRI. Because the tumor may have extended to the nasolacrimal duct, he was referred to the Yamaguchi University Department of Otolaryngology for treatment. We diagnosed an apocrine adenocarcinoma originating in the right lower eyelid. Since the cancer was non-metastatic, we performed right orbital total exenteration and partial maxillary resection as cancer treatment.Treatment of apocrine adenocarcinoma is often based on surgical resection; no consensus has been established regarding the usefulness of radiotherapy and chemotherapy for treatment. Apocrine adenocarcinoma is considered to have a relatively good prognosis. However, it is suggested that there may be some cases with high malignancy. Therefore, we consider that careful follow-up is necessary for patients after treatment for apocrine adenocarcinoma.

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Apocrine Adenocarcinoma of Lacrimal Sac Presenting as Chronic Dacryocystitis

Cited by 3 publications

References 10 publications

Primary apocrine adenocarcinoma of the orbit with lacrimal sac invasion

Primary apocrine adenocarcinoma of the orbit with lacrimal sac invasion

Cervical lymphocele: A rare complication following salvage surgery for ocular adnexal apocrine adenocarcinoma. A case report and review of the literature

A case of an apocrine adenocarcinoma originating in the eyelid

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