Apocrine Carcinoma, Adenopathies, and Raised TAG-72 Serum Tumor Marker

Abstract

To our best knowledge, this is the first case in which a tumor serum marker is associated with a cutaneous apocrine carcinoma, a fact that should be confirmed with further patients. Its use in the monitoring of this infrequent skin neoplasia is also noteworthy.

Tissue- and Serum-Associated Biomarkers of Hepatocellular Carcinoma

“…Tumor-associated glycoprotein 72 (TAG-72) is a cell membrane mucin-like glycoprotein complex, overexpressed in many of human adenocarcinomas but not in normal tissues. 43–45 In a study by Zhang et al, 46 it was demonstrated that TAG-72 is a new tissue biomarker in HCC that indicates the poor survival of patients (Fig. 5).…”

Primary cutaneous apocrine carcinoma: A challenging case report

“…Histologically, primary cutaneous apocrine carcinomas are invasive tumors, spreading from the reticular dermis to the subcutaneous fat tissue, forming clusters of tubular structures in different sizes and shapes [ 12 ]. Microscopically, they show considerable variability in their aspects; complex, glandular, papillary, tubular, cribriform, solid, and cord-like appearances have been reported.…”

Electrochemiluminescent Immune-Modified Electrodes Based on Ag2Se@CdSe Nanoneedles Loaded with Polypyrrole Intercalated Graphene for Detection of CA72-4

“…K is the slope of the calibration curve line). 31 Compared with the detection limit for time-resolved immunofluorometric assys (TR-IFMA) (0.55 U/mL), 32 immunoradiometric assay (0.8 U/mL) 33 and electrochemical immunosensors (0.1 U/mL), 34 the proposed ECL immunosensor has a lower detection limit. The lower detection limit may be the result of two factors: As shown in Figure 6B, the stability of the immunosensor was examined under the continuous scanning for 19 cycles for the detection of CA72-4 (0.1 U/mL).…”

“…K is the slope of the calibration curve line) . Compared with the detection limit for time-resolved immunofluorometric assys (TR-IFMA) (0.55 U/mL), immunoradiometric assay (0.8 U/mL) and electrochemical immunosensors (0.1 U/mL), the proposed ECL immunosensor has a lower detection limit. The lower detection limit may be the result of two factors: (1) the excellent conductivity and catalytic activity of PPy-NH 2 GO could greatly improve the ECL signal; (2) the large specific surface area of NH 2 GO after functionalized by PPy could fix a large amount of Ag 2 Se@CdSe.…”