APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study

Doshi, Mona D.; Li, Lihua; Naik, Abhijit S.; Thomas, Christie P.

doi:10.1016/j.xkme.2024.100828

Kidney Medicine

2024

DOI: 10.1016/j.xkme.2024.100828

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APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study

Mona D. Doshi,

Lihua Li,

Abhijit S. Naik

et al.

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Cited by 2 publications

References 33 publications

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APOL1 High-Risk Genotypes and Kidney Disease Risk in Middle-Aged Black Adults: More Questions Than Answers

Gutiérrez

2024

Kidney Medicine

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APOL1 High-Risk Genotypes and Kidney Disease Risk in Middle-Aged Black Adults: More Questions Than Answers

Gutiérrez

2024

Kidney Medicine

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Social Determinants of Health for Cardiovascular-Kidney-Metabolic Syndrome Among Patients With Diabetes

Belay,

Feleke,

Alemneh

et al. 2024

Journal of the Endocrine Society

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Context Cardiovascular Kidney-Metabolic (CKM) Syndrome is a recently introduced term that is a complex disease consisting of cardiovascular disease, renal disease, obesity, and diabetes. The association of social determinants of health with CKM Syndrome is not fully known. Objective We aimed to assess social determinants of health affecting cardiovascular kidney metabolic syndrome among adult patients with diabetes on follow-up at a tertiary hospital in Ethiopia. Method A cross-sectional hospital-based study was used. Data was collected using a Kobo toolbox and entered into SPSS version 29 for further analysis. Results A total of 422 adult patients with diabetes were included in this study. The mean ± SD age of the patients was 54.14±13.74 years. Fifty-two percent of the patients were male. In this study, 52.4% have cardiovascular kidney metabolic syndrome. Male patients (AOR: 1.73 (95% CI. 1.01, 2.94), lost to follow-up for more than a year due to lack of money (AOR: 2.69 95% CI, 1.01, 7.22), missed appointment due to lack of transportation in the past one year (AOR: 2.98 95% CI, 1.21, 7.33), patients with disability (AOR: 1.97, 95% CI, 1.12, 3.48), hypertension (AOR: 3.12 95% CI. 1.85, 5.28), obesity (AOR: 2.27, 95% CI, 1.17, 4.40), and retirement (AOR: 2.12, 95% CI, 1.04, 4.30) were more significantly associated with cardiovascular kidney syndrome. Conclusion More than half of patients have cardiovascular kidney-metabolic syndrome. More attention should be given to social determinants of health, including male gender, financial constraints, transportation issues, disability, and retirement.

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APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study

Cited by 2 publications

References 33 publications

APOL1 High-Risk Genotypes and Kidney Disease Risk in Middle-Aged Black Adults: More Questions Than Answers

APOL1 High-Risk Genotypes and Kidney Disease Risk in Middle-Aged Black Adults: More Questions Than Answers

Social Determinants of Health for Cardiovascular-Kidney-Metabolic Syndrome Among Patients With Diabetes

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