Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection

Li, Heng; Zhao, Xin; Zhang, Xinglong; Zheng, Huiwen; Wang, Yibin; Hou, Jinghan; Li, Jing; Zhao, Yurong; Peng, Shasha; Li, Yingyan; Zhang, Xin; Zhang, Yifan; Yang, Jinling; Zhang, Zihan; Shi, Haijing; Liu, Longding

doi:10.1007/s10495-024-01940-x

Apoptosis

2024

DOI: 10.1007/s10495-024-01940-x

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Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection

Heng Li,

Xin Zhao,

Xinglong Zhang

et al.

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Cited by 2 publications

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Inflammatory response to SARS-CoV 2 and other respiratory viruses

Viñán Garcés,

Cáceres,

Gómez

et al. 2024

Expert Review of Anti-infective Therapy

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Inflammatory response to SARS-CoV 2 and other respiratory viruses

Viñán Garcés,

Cáceres,

Gómez

et al. 2024

Expert Review of Anti-infective Therapy

View full text Add to dashboard Cite

A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation

Cheng,

Rui,

Wang

et al. 2024

J Biomed Sci

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Coronaviruses employ various strategies for survival, among which the activation of endogenous or exogenous apoptosis stands out, with viral proteins playing a pivotal role. Notably, highly pathogenic coronaviruses such as SARS-CoV-2, SARS-CoV, and MERS-CoV exhibit a greater array of non-structural proteins compared to low-pathogenic strains, facilitating their ability to induce apoptosis via multiple pathways. Moreover, these viral proteins are adept at dampening host immune responses, thereby bolstering viral replication and persistence. This review delves into the intricate interplay between highly pathogenic coronaviruses and apoptosis, systematically elucidating the molecular mechanisms underpinning apoptosis induction by viral proteins. Furthermore, it explores the potential therapeutic avenues stemming from apoptosis inhibition as antiviral agents and the utilization of apoptosis-inducing viral proteins as therapeutic modalities. These insights not only shed light on viral pathogenesis but also offer novel perspectives for cancer therapy.

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Apoptosis and pyroptosis in the nasal mucosa of Syrian hamster during SARS-CoV-2 infection and reinfection

Cited by 2 publications

References 35 publications

Inflammatory response to SARS-CoV 2 and other respiratory viruses

Inflammatory response to SARS-CoV 2 and other respiratory viruses

A glimpse into viral warfare: decoding the intriguing role of highly pathogenic coronavirus proteins in apoptosis regulation

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