Apoptotic effects of phenols from the twigs and leaves of Garcinia nujiangensis

Liu, Xiaojia; Lv, Tian-Meng; Sun, Shuhui; Guan, Qı; Hao, Jia-Hui; Zhou, Zhen-Chi; Niu, Shengli; Hua, Hui‐Ming

doi:10.1016/j.fitote.2023.105435

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2024

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Cited by 4 publications

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“…The plants of the genus are mainly distributed in Asia and Africa, among which 19 species are mainly native to Yunnan and Guangxi in China. [4,5] The chemical components mainly consist of xanthones, benzophenones, triterpenoids, etc., [6][7][8] and have exhibited pharmacological activities such as anticancer, hypoglycemic, antiparasitic, anti-HIV, and neuroprotective effects. [9][10][11][12][13] Garcinia pedunculata Roxb.…”

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confidence: 99%

α‐Glucosidase Inhibitory Components from Garcinia pedunculata Fruits

Zou,

Liu,

Liu

et al. 2024

Chemistry & Biodiversity

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From Garcinia pedunculata Roxb. fruits, two undescribed aromatic compounds including a benzofuran and a depsidone derivative, and a new natural product, together with four known compounds were isolated. Through the analysis of spectroscopic data, high resolution mass spectrum and calculated nuclear magnetic resonance, their structures were determined. The α‐glucosidase inhibitory activity of the isolates was evaluated. And compound 3 exhibited a moderate inhibitory effect on α‐glucosidase. The molecular docking of compound 3 was performed to elucidate the interaction with α‐glucosidase.

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