Apparent diffusion coefficients of benign and malignant salivary gland tumors. Comparison to histopathological findings

Matsushima, Nobuyoshi; Maeda, Masayuki; Takamura, Mitsuyuki; Takeda, Kan

doi:10.1016/j.neurad.2007.04.002

Cited by 97 publications

(80 citation statements)

References 12 publications

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“…In fact, normal adrenal glands show bright signal on DWI, although their small size makes direct ADC evaluation of normal adrenal tissue difficult. Matsushima et al (13) failed to differentiate between malignant and benign salivary gland tumors. The lower ADC value for Warthin's tumors compared with other benign tumors and higher ADC values for adenoid cystic carcinoma compared with other malignant tumors may be responsible for the considerable overlap of ADC values between malignant and benign tumors (13,36).…”

Section: Discussionmentioning

confidence: 99%

“…Matsushima et al (13) failed to differentiate between malignant and benign salivary gland tumors. The lower ADC value for Warthin's tumors compared with other benign tumors and higher ADC values for adenoid cystic carcinoma compared with other malignant tumors may be responsible for the considerable overlap of ADC values between malignant and benign tumors (13,36). Einarsdottir et al (37) also failed to differentiate benign and malignant soft tissue tumors using ADC values.…”

Section: Discussionmentioning

confidence: 99%

“…Many investigators have recently reported that body diffusion-weighted magnetic resonance imaging (DWI) may be useful not only for detecting malignant tumors and their metastatic spreads with high conspicuity (7)(8)(9)(10)(11), but also for tumor characterization (12)(13)(14)(15)(16)(17)(18)(19). Usually malignant tumors, including metastatic lesions, show bright signal on DWIs, and the apparent diffusion coefficient (ADC) values of malignant tumors are lower than the corresponding value of benign tumors.…”

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confidence: 99%

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Diagnostic utility of diffusion‐weighted MR imaging and apparent diffusion coefficient value for the diagnosis of adrenal tumors

Tsushima

Takahashi-Taketomi

Endo

2008

Magnetic Resonance Imaging

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Purpose:To determine the utility of diffusion-weighted MR imaging (DWI) for the diagnosis of adrenal tumors. Ϫ3 ; 0.51-1.23; p ϭ 0.14). Pheochromocytomas showed the higher mean ADC value (1.59 Ϯ 0.34*10 Ϫ3 ; 1.04 -1.96) compared with those of adenomas or metastatic tumors (P Ͻ 0.05 and P Ͻ 0.005, respectively). The mean SII of adenomas (62.1 Ϯ 17.9%; 14.5-88.4) was significantly higher than those of pheochromocytomas (4.0 Ϯ 10.0%; Ϫ19.6 -3.3; P Ͻ 0.005) or metastatic tumors (Ϫ1.5 Ϯ 11.7%; Ϫ18.3-8.2; P Ͻ 0.01). There was no correlation between ADC values and SII. Materials and Methods Conclusion:Although pheochromocytomas showed higher ADC values, we did not find that ADC value had diagnostic utility for differentiating adenomas and metastatic tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Diagnostic utility of diffusion‐weighted MR imaging and apparent diffusion coefficient value for the diagnosis of adrenal tumors

Tsushima

Takahashi-Taketomi

Endo

2008

Magnetic Resonance Imaging

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“…Anyway, in some cases, there is considerable overlap of ADC values, and DWI alone may not be sufficient to discriminate between benign and malignant salivary gland tumors [21,22].…”

Section: A Characterization Of Primary Tumorsmentioning

confidence: 99%

Difusion-Weighted MRI: from Brownian Motion to Head and Neck Tumor Characterization

Contreras¹,

Aguilera²,

Sánchez³

et al. 2017

IJIMAI

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“…5 In general, lesions and tumours with high cellularity or cellular swelling tend to present lower apparent diffusion coefficients (ADCs). Accordingly, ADC values have been reported to be lower in malignant tumours, as compared with benign tumours, [6][7][8] and inflammatory lesions. 9 For alterations of the salivary glands, MRI might be decisive for the diagnosis and can also contribute to defining the stage of the disease.…”

Section: Introductionmentioning

confidence: 99%

Diffusion-weighted MRI for differentiation between sialadenitis and pleomorphic adenoma

Terra¹,

Oliveira²,

Hernandez³

et al. 2017

Dentomaxillofacial Radiology

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Objectives: The aim of this study was to compare apparent diffusion coefficient (ADC) values from diffusion-weighted MRI (DWI) among normal salivary glands, cases with sialadenitis and cases with pleomorphic adenoma of major salivary glands. Methods: 22 patients (totalling 44 major salivary glands) diagnosed with either unilateral sialadenitis (on either parotid or submandibular gland) or parotid gland pleomorphic adenoma were selected. Contralateral non-affected glands (normal) were also analyzed. DW images were achieved using a spin-echo pulse sequence with a 1.5-T MRI device. Mean ADC values were compared among the three groups analyzed (contralateral normal glands, sialadenitis and pleomorphic adenoma). Results: The mean ADC values were significantly higher in cases of parotid sialadenitis (p 5 0.001), but not in cases of submandibular sialadenitis (p 5 0.466), as compared with the contralateral non-affected glands. Cases of pleomorphic adenoma presented the highest ADC values of the study. In addition, one-way ANOVA test revealed a significant difference among the three groups of parotid glands analyzed. Conclusions: Within the limitations of this study, the present results suggest that DWI allows for differentiation between parotid sialadenitis and pleomorphic adenoma.

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Apparent diffusion coefficients of benign and malignant salivary gland tumors. Comparison to histopathological findings

Cited by 97 publications

References 12 publications

Diagnostic utility of diffusion‐weighted MR imaging and apparent diffusion coefficient value for the diagnosis of adrenal tumors

Diagnostic utility of diffusion‐weighted MR imaging and apparent diffusion coefficient value for the diagnosis of adrenal tumors

Difusion-Weighted MRI: from Brownian Motion to Head and Neck Tumor Characterization

Diffusion-weighted MRI for differentiation between sialadenitis and pleomorphic adenoma

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