Appearances of choroidal osteomas with diagnostic imaging

Bloom, Philip; Ferris, John; Laidlaw, Alistair; Goddard, P

doi:10.1259/0007-1285-65-778-845

Cited by 7 publications

(3 citation statements)

References 13 publications

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“…OCT can indicate areas of variable reflectance, depending on the degree of tumour calcification. Decalcified areas are more hyperreflective (28). Recently introduced swept-source OCT (SS-OCT) enables a more accurate visualisation picture of the choroid and of pathology, including tumour type differentiation (29,30) (Fig.…”

Section: Discussionmentioning

confidence: 99%

Long-term clinical follow-up of patients with choroidal osteoma

Markiewicz¹,

Jędrychowska-Jamborska²,

Romanowska–Dixon³

2018

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Aim: To analyse symptoms, disease course, comorbidities, complications and treatment in eleven-year follow-up of patients with choroidal osteoma. Material and methods: Twelve eyes of 3 men and 8 women were analysed. Results: Choroidal neovascularization was observed in 5 eyes (41.6%), intraretinal fluid without features of choroidal neovascularization was observed in one case; there was also a single case of epiretinal membrane. Retinal pigment epithelium and Bruch membrane dystrophy alongside accumulation of subretinal fluid and intraretinal haemorrhage were observed in all cases of choroidal neovascularization, there was also one case of subretinal haemorrhage. Two patients with choroidal neovascularization were treated with anti-VEGF injections. The photodynamic therapy was used in one case. The majority (86%) of cases without choroidal neovascularization had visual acuity of 20/25 or better. In patients with choroidal neovascularization, the majority (80%) had visual acuity of 20/40 or lower. Anti-VEGF therapy (ranibizumab) improved visual acuity by 3 rows and stabilised it for a period of 20 months. Both discussed treatment methods accelerated decalcification, retinal pigment epithelial atrophy and subretinal fibrosis, which slowed down tumour growth. Conclusions: Anti-VEGF injections are the best option to inhibit tumour progression and should be used in cases with choroidal neovascularization.

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Section: Discussionmentioning

confidence: 99%

Long-term clinical follow-up of patients with choroidal osteoma

Markiewicz¹,

Jędrychowska-Jamborska²,

Romanowska–Dixon³

2018

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“…Bloom, Ferris, Laidlaw,.and Goddard (1992) described that the choroidal choristoma is not visualized on magnetic resonance imaging regardless of the tumor size.-They reported this as an important way to distinguish between a choroidal osteoma and a uveal malignant melanoma.…”

Section: Diagnostic Workupmentioning

confidence: 99%

Intraocular Choristoma

Kim

Henderson

2005

Seminars in Ophthalmology

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Choristomas have been reported in the orbit, cornea, conjunctiva, uvea, retina, and optic nerve. Many reports have described the choristoma mainly in the epibulbar area, but little is known of the choristoma that occurs intraocularly. We reviewed the literature and summarized the reports that described the choristoma inside the eyes. Iris, ciliary body, choroid, and optic nerve head are the commonly affected tissues. In the anterior uveal tissue, an ectopic lacrimal gland is common and appears as a pinkish, nodular, fleshy mass. Its clinical course largely depends on the enlargement of the accompanying cyst. Osseous choristoma is mainly found in the choroid in young female patients. Although it is regarded as a benign tumor, it grows progressively and can decrease visual function. Treatment consists of close observation and possibly surgical intervention. Fortunately, most of the intraocular choristomas do not need aggressive treatment.

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“…It may also provide information regarding the status of the overlying retina and the presence of SRF. FFA typically shows that an early hyperfluorescent picture with a mottled appearance is seen [10]. This is followed by late and persisting diffuse hyperfluorescence.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and Monitoring of Choroidal Osteoma through Multimodal Imaging

Empeslidis

Imrani

Konidaris

et al. 2014

Case Reports in Medicine

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A 16-year-old Caucasian female with a 6-month history of decreased visual acuity and metamorphopsia in the left eye is reported. The fundus of the left eye revealed a well defined lesion in the macula region. Diagnosis of choroidal osteoma was established using spectral domain optical coherence tomography (OCT), fundus fluorescein angiography (FFA), indocyanine green angiography (ICG), and B-scan ultrasonography. Subretinal fluid (SRF) and retinal pigment epithelium (RPE) detachment were noted in the absence of obvious classic choroidal neovascularisation (CNV). The patient was followed up for over 13 months without any treatment in the interim and the lesion was noted to have enlarged but visual acuity and SRF had remained stable. We report an interesting case where subretinal fluid was noted in the absence of evident choroidal neovascularisation and provide an example of the imaging modalities application in the era of “optical biopsy.”

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Appearances of choroidal osteomas with diagnostic imaging

Cited by 7 publications

References 13 publications

Long-term clinical follow-up of patients with choroidal osteoma

Long-term clinical follow-up of patients with choroidal osteoma

Intraocular Choristoma

Diagnosis and Monitoring of Choroidal Osteoma through Multimodal Imaging

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