Appendectomy in Sweden 1989–1993 Assessed by the Inpatient Registry

Blomqvist, Peter; Ljung, Håkan; Nyrén, Olof; Ekbom, Anders

doi:10.1016/s0895-4356(98)00065-1

Cited by 66 publications

(61 citation statements)

References 13 publications

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“…Studies from Europe and North America report decreasing rates of acute appendicitis, both in general1, 2, 3, 4 and in children5 6. There have been, however, more recent reports of stabilized7 8 or even increased9, 10, 11 incidence rates during the first decade of the 21st century.…”

Section: Introductionmentioning

confidence: 99%

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

et al. 2018

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BackgroundThe long‐term incidence of acute appendicitis has been reported to be declining in Europe and North America. Recent reports, however, indicate stabilized or even increased rates. The aim of this study was to investigate the present epidemiology of acute appendicitis and appendicectomy in a population‐based cohort of Swedish children.MethodsThe Swedish National Patient Register was queried for all children with acute appendicitis and/or appendicectomy in 1987–2013. Population‐based incidence rates were calculated. Rates were age‐ and sex‐adjusted, and analysed for temporal and regional trends.ResultsSome 56 774 children with acute appendicitis were identified, of whom 53 478 (94·2 per cent) underwent appendicectomy. The incidence rate of acute appendicitis declined by 43·7 per cent over 26 years, from 177·7 to 100·1 per 100 000 person‐years between 1987 and 2013. The most significant reduction was for non‐perforated appendicitis, from 138·5 to 68·4 per 100 000 person‐years between 1987 and 2009. The incidence rate of perforated appendicitis decreased from 28·0 to 19·9 per 100 000 person‐years and negative appendicectomies reduced from 48·5 to 3·6 per 100 000 person‐years during the study interval.ConclusionThe incidence rates of acute appendicitis and negative appendicectomy have reduced markedly in Swedish children over time, with significantly different trends amongst non‐perforated appendicitis and perforated appendicitis. The full explanation for the observed findings is unclear.

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Section: Introductionmentioning

confidence: 99%

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

et al. 2018

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“…The operative morbidity rates for non-perforated and perforated appendicitis are 20% and 30% respectively. (ref 2..8,27) The operative mortality rises with increased age as follows: <0.1% in patients less than 40 years of age, 2.6% in patients more than 60 years of age, 6.8% for octogenerians and 16.6% for nonagenarians (17). Hansson et al (3) found that the major complications were not significantly related to open or laparoscopic surgery.…”

Section: Efficacymentioning

confidence: 99%

“…The mortality rate for emergency appendicectomy ranges from 0.07 % to 0.7% in patients without perforation and 0.5% to 2.4% in those with (6). The chances of death in patients undergoing an emergency appendicectomy for acute appendicitis is up to seven times that of the general population of the same age and gender (17). The post-operative morbidity following emergency appendicectomy is 10 to 19% in those without perforation and reaches 12 to 30 % in patients with a perforation (18).…”

Section: Conservative Management Compared With Appendicectomymentioning

confidence: 99%

“…The rate of intestinal obstruction is slightly higher after a negative appendicectomy compared to a positive one. Literature studies have shown that the risk of death for patients undergoing an emergency appendicectomy is approximately seven times that of the general population of the same age and gender (17). The mortality rate for patients undergoing emergency appendicectomy for non-perforated and perforated appendicitis is 0.07 to 0.7% and 0.5-2.4% respectively (6).…”

Section: Efficacymentioning

confidence: 99%

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What Is the Role of Conservative Antibiotic Treatment in Early Appendicitis?

Chamisa¹

2012

Appendicitis - A Collection of Essays From Around the World

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“…It is one of the most common operations performed on the abdomen, with mortality rates ranging from 0.07% to 0.7% [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

A Meta-Analysis of Antibiotics Versus Surgery for the Treatment of Acute Appendicitis

Madanat¹,

Shaban²,

Naghawi³

et al. 2017

BIO

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Abstract:Appendectomy is the mainstay of treatment for acute appendicitis. Considering the complications of surgery, antibiotic treatment has also been gaining increasing interest in cases of acute appendicitis. This study aimed to compare the efficacy of antibiotics to surgery for acute uncomplicated appendicitis. The PubMed, Medline, Medscape and Cochrane databases were searched for studies comparing antibiotics versus surgery. The six outcome measures identified were thirty-day post-therapeutic peritonitis, length of hospital stay, prevalence of total complications, prevalence of normal appendix, prevalence of mean duration of pain and duration of disability. Five prospective RCTs with a total of 1430 patients (644 in the antibiotic group and 786 in the surgical group) were included in this study. Antibiotic treatment had a success rate of 75.3%. Regarding overall mean duration of disability, the antibiotic group had a significantly shorter duration of disability than that of the surgery group (P < 0.05). The total number of complications in the antibiotic group was 3.6% while that of the surgical group was 11.6%. The overall difference for mean duration of pain, and length of hospital stay between antibiotic therapy and surgery were not found to be statistically significant (P > 0.05). Although the conservative approach has a success rate lower than appendectomy, it is a possible alternative in certain clinical scenarios. Appendectomy remains the mainstay treatment for acute appendicitis. However, additional studies clarifying the certain etiologies of appendicitis that are responsive to antibiotic treatment are needed to further support its use.

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Appendectomy in Sweden 1989–1993 Assessed by the Inpatient Registry

Cited by 66 publications

References 13 publications

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

Population-based cohort study on the epidemiology of acute appendicitis in children in Sweden in 1987-2013

What Is the Role of Conservative Antibiotic Treatment in Early Appendicitis?

A Meta-Analysis of Antibiotics Versus Surgery for the Treatment of Acute Appendicitis

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