2003
DOI: 10.1053/jpsu.2003.50052
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Appendicitis in children: A ten-year update of therapeutic recommendations

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Cited by 105 publications
(75 citation statements)
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References 27 publications
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“…However, most of these reports predate the era of current antimicrobial therapy, which has led to decreased rates of wound infections. Many studies in the 80s and 90s reported low rates of infection using primary closure (PC), suggesting that such management might be safely and successfully used [4,[7][8][9][10][11][12][13][14][15][16][17][18].…”
Section: Background/purposementioning
confidence: 99%
“…However, most of these reports predate the era of current antimicrobial therapy, which has led to decreased rates of wound infections. Many studies in the 80s and 90s reported low rates of infection using primary closure (PC), suggesting that such management might be safely and successfully used [4,[7][8][9][10][11][12][13][14][15][16][17][18].…”
Section: Background/purposementioning
confidence: 99%
“…β-Lactam antibiotics mimic the D-Ala-DAla site, thereby irreversibly inhibiting PBP crosslinking of peptidoglycan. 16 This study showed the common oral antibiotic that been widely used in the community are amoxicillin, ampicillin, trimethropim/ sulphametoxazole, and tetracyclin. Most of them were resistant to specific isolated bacteria with 25-87% resistant percentage.…”
Section: Discussionmentioning
confidence: 88%
“…Congestion leads to vascular thrombosis and mucosal damage, which ultimately causes microbial invasion into the appendix wall followed by inflammation. 12,13 As the disease progresses, necrosis and gangrene develop in the appendix that cause perforation and greatly induce peritoneal irritation. At this stage, the pain may radiate and intensify over a diffuse area of the abdomen.…”
Section: Discussionmentioning
confidence: 99%