Appendicopathy. A report of eight cases

Ruiz, J.; Rı́os, Antonio; Oviedo, María Isabel; Rodrı́guez, José Manuel; Parrilla, Pascual

doi:10.17235/reed.2017.4520/2016

Cited by 6 publications

(6 citation statements)

References 15 publications

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“…The incidence of appendicitis obliterans ranges between 0.16% to 0.81% in adult population as per different studies [4,5] while incidence in paediatric population is about 0.25%. The disorder is more common in second decade of life rather than first decade and is more common in female population [6].…”

Section: What Is the Incidence Of Appendicitis Fibrous Obliterans?mentioning

confidence: 93%

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Pristine Normal Looking Appendix on Diagnostic Laparoscopy-A Management Dilemma

Rangan¹,

Samee²

2021

Int J Surg Res Pract

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What is the Clinical Presentation?The abdominal pain of appendicitis fibrous obliterans is very similar to acute appendicitis. However, other systemic symptoms like fever, anorexia might be variable. History and clinical examination do not make it possible to distinguish appendicitis fibrous obliterans with acute appendicitis [8]. Though the diagnosis of appendicitis fibrous obliterans is entirely incidental, one

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Section: What Is the Incidence Of Appendicitis Fibrous Obliterans?mentioning

confidence: 93%

“…A study that identified an incidence of 0.16% of neurogenic appendicopathy followed up all patients for a mean period of 73.2 ± 28 months concluded that all patients who underwent remained asymptomatic [5].…”

Section: What Is Appendicitis Fibrous Obliterans?mentioning

confidence: 99%

Pristine Normal Looking Appendix on Diagnostic Laparoscopy-A Management Dilemma

Rangan¹,

Samee²

2021

Int J Surg Res Pract

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“…The term “chronic appendicitis” is one of several terminologies used to describe cases of NA with fibrosis, but lacking an acute inflammatory reaction. NA represents from 0.16% [ 8 ] to17.1% of all cases of surgically treated appendicitis [ 5 , 9 , 10 ]. It is more common in females than in males.…”

Section: Introductionmentioning

confidence: 99%

“…It is more common in females than in males. It is common in the third decade (27.8 ± 12 years) of life [ 8 ], and after 45 years of age, but uncommon in the first decade of life [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Neurogenic Appendicitis: A Reappraisal of the Clinicopathological Features and Pathogenesis

2022

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In 1921; Masson and Maresch first coined the term “neurogenic appendicitis (NA)” to describe “neuroma-like” lesions in the appendix. To date, our knowledge about NA is limited; therefore, we conducted a comprehensive analysis of the literature (1921 to 2020) to examine the clinicopathological features of NA. We also addressed the pathophysiology of acute abdominal pain and fibrosis in this entity. We performed a meta-analysis study by searching the PubMed database, using several keywords, such as: “appendix,” “neurogenic,” “obliterative,” “neuroma,” “fibrous obliteration,” “appendicopathy,” and “appendicitis.” Our study revealed that patients with NA usually present clinically with features of acute appendicitis, bud2t they have grossly unremarkable appendices. Histologically, the central appendiceal neuroma was the most common histological variant of NA, followed by the submucosal and intramucosal variants. To conclude, NA represents a form of neuroinflammation. The possibility of NA should be considered in patients with clinical features of acute appendicitis who intraoperatively show a grossly unremarkable appendix. Neuroinflammation and neuropeptides play roles in the development of pain and fibrosis in NA.

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“…Appendiceal neuroma consist of a proliferation of fusiform cells in a myxoid background comprising of connective tissue, fatty tissue and eosinophils. These fusiform cells are positive 14,15,16,17 for S-100 protein and neuron-specic enolase.…”

mentioning

confidence: 98%