Applicability of bacterial cellulose as an alternative to paper points in endodontic treatment

Silva

et al. 2016

Carbohydrate Polymers

290

133

Bacterial cellulose (BC) produced by some bacteria, among them Gluconacetobacter xylinum, which secrets an abundant 3D networks fibrils, represents an interesting emerging biocompatible nanomaterial. Since its discovery BC has shown tremendous potential in a wide range of biomedical applications, such as artificial skin, artificial blood vessels and microvessels, wound dressing, among others. BC can be easily manipulated to improve its properties and/or functionalities resulting in several BC based nanocomposites. As example BC/collagen, BC/gelatin, BC/Fibroin, BC/Chitosan, etc. Thus, the aim of this review is to discuss about the applicability in biomedicine by demonstrating a variety of forms of this biopolymer highlighting in detail some qualities of bacterial cellulose. Therefore, various biomedical applications ranging from implants and scaffolds, carriers for drug delivery, wound-dressing materials, etc. that were reported until date will be presented.

Section: Dental/oral Implantsmentioning

confidence: 97%

A multipurpose natural and renewable polymer in medical applications: Bacterial cellulose

Silva

et al. 2016

Carbohydrate Polymers

290

133

“…In veterinary medicine, studies report that bacterial cellulose (BC) was used in the bioengineering of hard (Saska et al 2011;Yoshino et al 2013), fibrocartilaginous (Tanaka et al 2014) and soft tissue engineering (Bodin et al 2010;Lima et al 2017). Bacterial cellulose is a polysaccharide used as scaffold in various medical fields (Rajwade et al 2015).…”

mentioning

confidence: 99%

“…Newly elaborated scaffolds used as tissue replacement are gaining the attention of biomedical research. Studies on biomaterials concluded that BC (Neto and Dolci 2010;Kim et al 2013;Yoshino et al 2013) or BC composites (Saska et al 2011;Pigossi et al 2015) could replace both hard (Saska et al 2012;Yoshino et al 2013;Suwandi et al 2015) and soft tissues (Almeida et al 2014;Scherner et al 2014;Xu et al 2014).…”

mentioning

confidence: 99%

Applications of bacterial-synthesized cellulose in veterinary medicine – a review

et al. 2019

Tissue engineering promotes tissue regeneration through biomaterials that have excellent properties and have the potential to replace tissues. Many studies show that bacterial cellulose (BC) might ensure tissue regeneration and substitution, being used for the bioengineering of hard, cartilaginous and soft tissues. Bacterial cellulose is extensively used as wound dressing material and results show that BC is a promising tissue scaffold (bone, cardiovascular, urinary tissue). It can be combined with polymeric and non-polymeric compounds to acquire antimicrobial, cell-adhesion and proliferation properties. To ensure proper tissue regeneration, the material has to be: biocompatible, with minimum tissue reaction and biodegradability; bio-absorbable, to promote tissue development, cellular interaction and grow; resistant to support the weight of the newly formed tissue. Its versatile structure, physical and biochemical properties can be adjusted by adapting the bacteria culturing conditions. The main biomedical applications seem to be as hard (bone, dental), fibrocartilaginous (meniscal) and soft tissue (skin, cardiovascular, urinary) substituents. This paper reviews the current state of knowledge, challenges and future applications of BC and its biomedical potential in veterinary medicine. It was focused on the main uses in regeneration and scaffold tissue replacement and, although BC showed promising results, there is a lack of successful results of BC use in clinical practice. Most studies were performed only at experimental level and further research is needed for BC to enter clinical veterinary practice.

“…It is biocompatible and is already used for tissue scaffolds in bioengineering and as a substitute for plant cellulose materials in wound dressings. BC points have fibrillar structures with diameters on the nanoscale (several tens of nanometres), as opposed to the approximately 10 lm diameter of paper point fibril bundles and, possibly due to their fibrillar dimensions and absence of contaminating polymers, induce a milder and less prolonged inflammatory reaction (Yoshino et al 2013). Further development of absorbent BC endodontic points may eliminate the risk of biological hazard from cellulose fibre shedding.…”

Section: Discussionmentioning

confidence: 99%

Paper points revisited: risk of cellulose fibre shedding during canal length confirmation

Brown

2016

Int Endodontic J