Liquid loading in gas wells may slash production rates, shorten production life, or even stop production. In order to reveal the mechanism of liquid loading in gas wells and predict its critical flowrates, theoretical research and laboratory experiments were conducted in this work. A new model of liquid-film reversal was established based on Newton’s law of internal friction and gas–liquid two-phase force balance, with the critical reverse point obtained using the minimum gas–liquid interface shear force method. In this model, the influences of the pipe angle on the liquid film thickness were considered, and the friction coefficient of the gas–liquid interface was refined based on the experimental data. The results showed that the interfacial shear force increases by increasing the liquid superficial velocity, which leads first to an increase of the critical liquid-carrying gas velocity and then to a decrease, and the critical production also decreases. With 0° as the vertical position of the pipeline and an increase of the inclination angle, the critical liquid-carrying velocity first increases and then decreases, and the maximum liquid-carrying velocity appears in the range of 30–40°. In addition, the critical liquid-carrying gas velocity is positively correlated with the pipe diameter. Compared with the previous model, the model in this work performed better considering its prediction discrepancy with experiment data was less than 10%, which shows that the model can be used to calculate the critical liquid-carrying flow rate of gas wells. The outcome of this work provides better understanding of the liquid-loading mechanism. Furthermore, the prediction model proposed can provide guidance in field design to prevent liquid loading.