Application and Immunogenicity of Aptamers in Cancer Therapy

Abstract

Aptamers are short single-stranded nucleic acid (DNA or RNA) or peptide sequences with a unique three-dimensional structure that bind to their targets with high specificity and affinity. Aptamers’ small size, fast and cheap production process, low immunogenicity, and high stability have made them attractive molecules in some fields of research, especially in the design of new diagnostic and therapeutic pathways. This review article discusses aptamers’ applications and immunogenic properties in the pharmaceutical sciences.