Application of 3D Simulation Software in Chemotherapy and Hepatoblastoma Surgery in Children

Liu, Jie; Xiu, Wenli; Duan, Guangqi; Dong, Qi

doi:10.3389/fsurg.2022.908381

Cited by 7 publications

(7 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CAS is a 3D reconstruction based on CT data that can be used for precise preoperative evaluation and surgical planning by reconstructing organs and tumors and tracking arteries. It can display the adjacent relationship between the tumor and surrounding vascular organs in a 3D, dynamic and overall way[ 17 ]. The CAS of this patient clearly showed that the giant retroperitoneal tumor completely encased the inferior mesenteric artery with a clear vessel shape and normal tube wall shape.…”

Section: Discussionmentioning

confidence: 99%

Computer-assisted rescue of the inferior mesenteric artery in a child with a giant ganglioneuroblastoma: A case report

Xiu¹,

Liu²,

Zhang³

et al. 2023

World J Gastrointest Surg

Self Cite

View full text Add to dashboard Cite

BACKGROUND Ganglioneuroblastoma (GNB) is a peripheral neuroblastoma (NB) with malignant degree between highly malignant NB and benign ganglioma (GN). Pathology is the gold standard of diagnosis. Although GNB is not uncommon in children, biopsy alone may lead to an inaccurate diagnosis, especially for giant tumors. However, surgical resection may be associated with significant complications. Here, we report a case of computer-assisted surgical resection of a giant GNB in a child and successful rescue of the inferior mesenteric artery. CASE SUMMARY A 4-year-old girl was admitted to our department for a giant retroperitoneal lesion, which was considered to be an NB by her local hospital. The symptoms of the girl disappeared spontaneously without treatment. On physical examination, a mass of about 10 cm × 7 cm could be palpated in her abdomen. Ultrasonography and contrast-enhanced computed tomography performed in our hospital also showed an NB, and there was a very thick blood vessel inside the tumor. However, aspiration biopsy revealed GN. Surgical resection is the best treatment option for this giant benign tumor. For precise preoperative evaluation, three-dimensional reconstruction was performed. It was clear that the tumor was close to the abdominal aorta. The superior mesenteric vein was pushed forward, and the inferior mesenteric artery passed through the tumor. Because GN generally does not invade blood vessels, we split the tumor with a CUSA knife during the operation and found that there was indeed a straight and intact vascular sheath. Arterial pulsation was observed in the completely exposed inferior mesenteric artery. The pathologists interpreting the tissue finally diagnosed it as a mixed GNB (GNBi), which is more malignant than GN. However, both GN and GNBi usually have a good prognosis. CONCLUSION This was a case of successful surgical resection of a giant GNB, and aspiration biopsy underestimated the pathological staging of the tumor. Preoperative three-dimensional reconstruction assisted with the radical resection of the tumor and rescue of the inferior mesenteric artery.

show abstract

Section: Discussionmentioning

confidence: 99%

Computer-assisted rescue of the inferior mesenteric artery in a child with a giant ganglioneuroblastoma: A case report

Xiu¹,

Liu²,

Zhang³

et al. 2023

World J Gastrointest Surg

Self Cite

View full text Add to dashboard Cite

show abstract

“…In this study, the CAS‐assisted group experienced less intraoperative blood loss and a lower blood transfusion rate than the control group. The 3D reconstruction image is more clearly illustrates the adjacency between the tumor and the blood vessels, whether it invades the blood vessels, and the variation of the blood vessels when compared to the 2D plane image 12 ,. 14 , 19 Compared with other 3D reconstruction software, 12 , 20 the entire process of 3D reconstruction with the Hisense CAS system takes roughly 20 min, so it takes less time and has higher work efficiency.…”

Section: Discussionmentioning

confidence: 99%

“…The 3D reconstruction image is more clearly illustrates the adjacency between the tumor and the blood vessels, whether it invades the blood vessels, and the variation of the blood vessels when compared to the 2D plane image 12 ,. 14 , 19 Compared with other 3D reconstruction software, 12 , 20 the entire process of 3D reconstruction with the Hisense CAS system takes roughly 20 min, so it takes less time and has higher work efficiency. Therefore, it is very suitable for more urgent preoperative planning cases.…”

Section: Discussionmentioning

confidence: 99%

“…5 However, the complex anatomical spatial structure and extensive vascular and nerve structures of the mediastinum poses a great challenge for surgical operation. 6,7 Computer-assisted surgery system (CAS) has been increasingly used in clinical surgical treatment, due to its advantages of threedimensional (3D) visualization, 8 accurate vascular reconstruction in children, 9,10 3D model surgical simulation, 11 3D data automatic calculation, 9,11,12 and so on. Based on patients' computed tomography (CT) or MRI DICOM files, CAS enables rapid and simple rendering of high-definition 3D images of organs, tumors and vessels, 13 making clinical operation more accurate.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Application of computer‐assisted surgery in pediatric mediastinal tumor surgery

Liu

Xia

Duan

et al. 2022

Robotics Computer Surgery

Self Cite

View full text Add to dashboard Cite

Background: Computer-assisted Surgery system (CAS) is an effective medical imaging simulation tool, which is widely used in preoperative planning of surgery. The objective of this study is to investigate the clinical application of CAS in pediatric mediastinal tumor resection. Methods: This retrospective study investigated 74 children who underwent mediastinal tumor resection between June 2008 and June 2022 at the pediatric surgical center of the Affiliated Hospital of Qingdao University and Qingdao Women and Children's Hospital. Preoperative chest computed tomography imaging was performed on all children. A total of 44 children (the CAS-assisted group) underwent clinical image 3D reconstruction and preoperative simulation using Hisense CAS.The control group consisted of 30 children who underwent a conventional procedure without CAS. The demographic, preoperative, and complication data were analyzed and compared between the two groups. t-test, Mann-Whitney U test, X 2 test, or Fisher's exact test were used accordingly in this study during analysis. Results:The median operative duration was 119.00 min in the CAS-assisted group and 140.50 min in the control group. The median intraoperative blood loss of the CAS-assisted group and the control group was 14.00 and 31.00 ml respectively.Relative to the control groups, the CAS-assisted group experienced shorter operative duration time (p = 0.041), and less intraoperative blood loss (p < 0.001). The difference in postoperative drain indwelling between the CAS-assisted group (median:4.00 days) and the control group (median:7.00 days) reached a statistical significance (p = 0.001). And the duration of hospitalization after the operation for the CAS-assisted group (median:7.00 days) was shorter than that for the control group (median:9.00 days) (p = 0.001). No significant difference could be found in the rate of blood transfusion (p = 0.258) and the incidence of postoperative complications (p = 0.719) between the two groups. Conclusion:Hisense CAS could effectively assist surgeons to clearly determine the anatomical site of tumors and provide accurate preoperative simulation for surgeons, so as to assist surgeons to specify effective surgical plans for patients.

show abstract

“…Hisense CAS can also display the overall 3D anatomical relationship and pipeline variations in a semitransparent and interactive way, calculate the distance between any two points and the angle of travel of any blood vessel, the range of innervation or drainage, and the volume of organs and tumors, and provide other information that cannot be obtained from traditional 2D images. In addition, a cloud-based 3D visualization platform for precision surgery based on B/S architecture was constructed to realize the data interactions between the PC terminal browser and CAS and to store, manage and share 2D and 3D image data (Figure 1) [8,9].…”

Section: Research and Development Of Cas Based On Artificial Intellig...mentioning

confidence: 99%

Application of Computer-Assisted Surgery System Based on Artificial Intelligence in Pediatric Precise Oncological Surgery

Xiu¹,

Hao²,

Xia³

et al. 2023

Artificial Intelligence

Self Cite

View full text Add to dashboard Cite

Pediatric oncological surgery is difficult and challenging, especially in children with malignant solid tumors. Compared with adults, children have immature organs, thin blood vessels, and poor surgical tolerance. Moreover, pediatric malignant solid tumors are often huge, complex in location, fast-growing, and highly malignant. With artificial intelligence and machine learning breaking through many bottlenecks, computer-assisted precision medicine has also taken a quantum leap forward. Ten years ago, Professor Dong’s group invented the Computer-assisted Surgery System (Hisense CAS). Now, this three-dimensional (3D) visualization technology based on artificial intelligence has been used for pediatric precise oncological surgery and has been upgraded to version 5.0. Hisense CAS was developed based on enhanced pediatric CT data, so it has advantages in displaying pediatric solid tumors. CAS can display the adjacent relationships of the tumor with the surrounding tissues (especially the compressed blood vessels) in a 3D, dynamic, and complete manner through rapid and accurate 3D reconstruction of organs, tumors, and blood vessels. Then, precise preoperative evaluations and surgical planning can be carried out. This chapter focuses on individualized computer-assisted surgical planning and progress in common and complex pediatric tumors (such as malignant liver tumors, retroperitoneal tumors, and mediastinal tumors) and introduces experience in improving the resectability of tumors and reducing surgical complications.

show abstract

Application of 3D Simulation Software in Chemotherapy and Hepatoblastoma Surgery in Children

Cited by 7 publications

References 34 publications

Computer-assisted rescue of the inferior mesenteric artery in a child with a giant ganglioneuroblastoma: A case report

Computer-assisted rescue of the inferior mesenteric artery in a child with a giant ganglioneuroblastoma: A case report

Application of computer‐assisted surgery in pediatric mediastinal tumor surgery

Application of Computer-Assisted Surgery System Based on Artificial Intelligence in Pediatric Precise Oncological Surgery

Contact Info

Product

Resources

About