Along with the popularization and expanding influence of Internet applications, Web 3D is born from various mature technologies driven by the demand for commercial interests in the Internet. This study designs an interactive intelligent design method for indoor environment space based on Web 3D, which has cross-platform and high-performance graphic drawing capability and covers indoor lighting material transformation, smooth switching of viewpoints, zooming of areas, and other interactive modes. It has cross-platform and high-performance graphic drawing capabilities and covers indoor lighting material change, smooth switching of viewpoints, area zoom, and other features. Based on the visual perception characteristics of the human eye, we obtain the user’s most realistic experience of the color of the indoor space and then construct the virtual indoor environmental space through the Web 3D system, and carry out a visual analysis of the indoor space under different materials and colors. The results show that under the visual analysis of Web 3D, the optimal distribution of color luminance values affecting the visual psychology of indoor environmental space is between 30.5 and 68.9nit, with a mean value of 49.59nit. The results can establish a favorable basis for the later indoor color configuration, which is in line with the visual characteristics of the human eye in indoor color configuration design practice.