Application of a Tetraamino Cobalt(II) Phthalocyanine Modified Screen Printed Carbon Electrode for the Sensitive Electrochemical Determination of L‐Dopa in Pharmaceutical and Biological Samples

Georgescu, Ramona; Stefanov, Cristina; Staden, Jacobus Frederick van; Staden, Raluca-Ioana Stefan van

doi:10.1002/elan.202100132

Cited by 5 publications

(2 citation statements)

References 53 publications

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“…The fitted values of the R ct decreased with the sequence AuNP (260 Ω) > p-NiTsPc (135 Ω) > p-NiTsPc/AuNP (97 Ω). All modifications showed good conductivity and superior electron transfer in relation to the bare SPCE, as expected for AuNPs [43,44] and phthalocyanine conducting films [45][46][47]. However, the SPCE/p-NiTsPc/AuNP (R ct = 97 Ω) showed a synergetic effect decreasing 84% the R ct when compared to the bare SPCE (597 Ω), i.e., increasing significantly the conductivity of the electrode surface.…”

Section: Cyclic Voltammetry and Electrochemical Impedance Spectroscopymentioning

confidence: 64%

Nickel Tetrasulfonated Phthalocyanine Decorated with AuNP as a Double Sensorial Platform: SERS and Electrochemical

et al. 2023

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The development of materials for multiple applications is a challenge in the fields of technology and materials science. In this work, screen-printed carbon electrodes (SPCEs) were modified with an electropolymerized nickel tetrasulfonated phthalocyanine film (polymeric-NiTsPc = p-NiTsPc) decorated with gold nanoparticles (AuNP). The modified SPCEs were applied as a sensing platform for analysis via electrochemical and surface-enhanced Raman scattering (SERS) spectroscopy. The SPCEs modification was based on the potential cycling firstly in a NiTsPc solution and then in an AuHCl4 solution, with the fast formation of spherical AuNP through the p-NiTsPc film surface. The modified electrode based on SPCE/p-NiTsPc/AuNP showed a synergetic effect in voltammetric measurements in [Fe(CN)6]3−/[Fe(CN)6]4− probe as well as an electrocatalytic effect in the presence of dopamine. The calibration curve towards dopamine detection presented a linear range from 1 to 10 μmol/L with a limit of detection of 0.73 μmol/L. The spectroelectrochemistry measurements combining SERS and the applied potential of −60 mV showed that the SPCE/p-NiTsPc/AuNP and SPCE/AuNP can be powerfully used as a dual sensing platform for dopamine detection. In the case of SPCE/p-NiTsPc/AuNP, p-NiTsPc plays an important role in facilitating electron transfer during the electrochemical reaction, while AuNP is crucial for obtaining SERS signals for dopamine detection.

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Section: Cyclic Voltammetry and Electrochemical Impedance Spectroscopymentioning

confidence: 64%

Nickel Tetrasulfonated Phthalocyanine Decorated with AuNP as a Double Sensorial Platform: SERS and Electrochemical

et al. 2023

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“…Electrochemical approaches are highly advantageous in the advancement of sensors for applications pertaining to health. , Electrochemical sensors are utilized to quantify the current generated by the working electrode, relying on the electrochemical redox mechanism of an analyte. The sensors are capable of measuring the concentration of a specific analyte, in this case, thiamine, within the electrolyte solution.…”

Section: Introductionmentioning

confidence: 99%

Disposable Stochastic Miniplatforms for Simultaneous Recognition and Determination of Vitamins B5, B7, and B9 in Food and Pharmaceutical Compounds

Stefan-van Staden,

Rasit,

Gheorghe

et al. 2024

ACS Omega

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Vitamins are essential for supporting daily physiological functions and are crucial for metabolic processes, including preventing vascular events and delaying the progression of diabetic nephropathy. The specific assessment of food and pharmaceutical compound quality requires the highly sensitive evaluation of vitamins B5, B7, and B9. Therefore, it is necessary to have a fast screening method for multivitamin tablets, pharmaceutical tablets, water, food, including raw egg yolk, and biological fluids, including urine, in order to ensure the precise identification and measurement of vitamins B5, B7, and B9. This paper introduces a novel disposable stochastic miniplatform that utilizes an incorporated 2D stochastic sensor to be able to simultaneously assay the three vitamins. Cobaltphthalocyanine was used to modify the carbon film of the 2D sensor. High sensitivities (of 10 2 −10 8 s −1 g −1 mL magnitude order) and low detection limits (of pg mL −1 magnitude order) were recorded for the disposable stochastic miniplatforms. The validation procedure involved the utilization of pharmaceutical tablets, supplement tablets, water samples, food samples, including raw egg yolk, and biological samples, specifically urine. The disposable stochastic miniplatforms demonstrate cost-effectiveness and suitability for the fast screening tests, with a time frame of 6 min, across a range of samples, a capacity of over 150 measurements, and an endurance of up to one month. Recovery values higher than 94.00% with RSD (%) values lower than 1.00 were recorded.

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Anthraquinone/Activated Carbon Electrochemical Sensor and its Application in Ofloxacin Analysis

Zhong,

Chen,

Zheng

et al. 2024

Electroanalysis

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Ofloxacin (OFL) has antibacterial and anti‐inflammatory effects on respiratory tract infection, skin soft tissue infection and urogenital tract infection caused by sensitive bacteria. In this study, an electrochemical sensor on account of glassy carbon electrode (GCE) and anthraquinone (AQ)/Vulcan XC‐72 (C) composite was prosperity prepared for the determination of ofloxacin (OFL) drug. The morphology and structure of C/20%AQ composites were characterized by SEM. The electrochemical behavior of OFL on the C/20%AQ/GCE sensor was tested using differential pulse voltammetry (DPV) and cyclic voltammetry (CV). The consequences indicate that the linear response of the sensor to OFL

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Application of a Tetraamino Cobalt(II) Phthalocyanine Modified Screen Printed Carbon Electrode for the Sensitive Electrochemical Determination of L‐Dopa in Pharmaceutical and Biological Samples

Cited by 5 publications

References 53 publications

Nickel Tetrasulfonated Phthalocyanine Decorated with AuNP as a Double Sensorial Platform: SERS and Electrochemical

Nickel Tetrasulfonated Phthalocyanine Decorated with AuNP as a Double Sensorial Platform: SERS and Electrochemical

Disposable Stochastic Miniplatforms for Simultaneous Recognition and Determination of Vitamins B5, B7, and B9 in Food and Pharmaceutical Compounds

Anthraquinone/Activated Carbon Electrochemical Sensor and its Application in Ofloxacin Analysis

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