Application of advanced platelet-rich fibrin for through-and-through bony defect during endodontic surgery: Three case reports and review of the literature

Abstract

BACKGROUND The use of advanced platelet-rich fibrin (A-PRF) membranes for guided bone and tissue regeneration in through-and-through defects after endodontic surgery was explored in three cases. CASE SUMMARY Herein, three patients presented to the endodontic clinic suffering from apical periodontitis, associated with large bone resorption and related to previously endodontically treated teeth. Periapical surgery was indicated in these cases and the osteotomy site was covered by A-PRF membrane. Cone-beam computed tomography (CBCT) was used to assess the cases before and after the surgery. CONCLUSION Four months post-surgery, the recall CBCT scan showed complete obliteration of the osteotomy with newly formed bone. A-PRF membrane showed promising results and was an advantageous addition to surgical endodontic treatment.

Platelet-rich fibrin as an apical barrier for MTA placement in the treatment of teeth with open apices: a pilot study

“…The PRF membrane with RCF clot of 145 used in the present pilot study was constructed with a box instrument accompanied by a centrifuge machine [ 26 ]. Steel plane of the box cover and the basement proper designate the PRF membrane once it is withdrawn from the sterile vacuum tube.…”

“…Steel plane of the box cover and the basement proper designate the PRF membrane once it is withdrawn from the sterile vacuum tube. The dimension of the piece of the PRF membrane correlates with the size of the apical foramen for each circumstance and facilitates the manipulation of the insertion through the foramen [ 26 ]. The size of the plugger is suitable for the apical foramen because it does not damage the delicate dentinal wall of the apical third further.…”

“…PRF membrane formation was confirmed using the cover of the accompanying box in the kit without further requirement. A PRF piece cut from the PRF membrane from the large membrane facilitates the insertion of the piece over the large apical foramen under a dental microscope [ 17 , 18 , 26 ]. The technique is sufficiently tough and small for manipulating material in the complicated periapical area.…”

“…Manipulating the MTA with an apical lesion is challenging. Although the operator can have excellent vision, magnification, and illumination under a dental microscope, preventing the extrusion of MTA is difficult [ 17 , 18 , 26 ].…”

“…However, MTA is very popular, while PRF is less popular than the former in endodontics [ 10 , 17 , 18 ]. PRF is encountered mostly in surgical therapy, such as oral surgery, periodontal open flap management, and implant procedures [ 13 , 26 ].…”