Application of aeration‐assisted homogeneous liquid–liquid microextraction procedure using Box–Behnken design for determination of curcumin by HPLC

Abstract

A simple, efficient, and rapid sample preparation method based on aeration‐assisted homogeneous liquid–liquid microextraction was developed for determination of curcumin in food samples by high‐performance liquid chromatography. The centrifuge step has been eliminated in this procedure. The effects of some variables, such as pH, volume of extraction solvent, extraction time, and salt effect, were studied through a Box–Behnken design method. Under the optimum conditions, calibration curves of curcumin were linear in the range of 0.08‐4000 μg/mL with R2 = 0.997. Limit of detection and relative standard deviation were 0.019 μg/mL and 3.01%, respectively. The preconcentration factor achieved was 166. The proposed method was successfully applied to determination of curcumin in various food samples.

Nitrogen-doped fluorescence carbon dots as multi-mechanism detection for iodide and curcumin in biological and food samples

“…At present, various detection techniques have been successfully developed to determinate iodide ions and curcumin, such as chromatography [ 13 , 14 ], capillary electrophoresis [ 15 , 16 ], electrochemistry [ 17 , 18 ], and so on. Although these methods possess high accuracy and satisfactory sensitivity, they still display some disadvantages, such as sophisticated instrumentation, complicated sample pretreatment, tedious operation procedures, and unstable electrodes, which are limited to some extent to apply extensively.…”

Spectrophotometric determination of phenol impurity in phenoxyethanol and phenol index of drinking water and municipal wastewater effluent after salting-out assisted liquid phase microextraction (SA-LPME)

“…These factors include buffer (A), 4-AAP (B), potassium hexacyanoferrate (C), and NaCl (D). The following equation was used within the BBD for determining the number of required experiments (N) [ 31 ]. Where the number of central points is C 0 , and the variable number is k .…”

Validation of an innovative analytical method for simultaneous quantification of curcumin and fluconazole using high‐performance liquid chromatography from nanostructured lipid carriers

“…A Waters™ e2695 liquid chromatography with a PDA/ UV-visible detector was used. The mobile phase was determined based on the studies by Fonseca-Santos et al [30], Abdel-Moety et al [32], and Khorshidi et al [37], with modifications. The detector was set to 261 nm and the peak areas were automatically integrated using Empower software.…”