Application of allograft bone transplantation in bone tumour surgery

Abstract

Objective: To discuss the scope, effect, rejection reaction, etc. of applying allograft bone transplantation in bone tumour surgery. Method: 120 cases of allogeneic bone transplantation were used in bone tumour surgery from October 1983 to March 2003, including 102 cases of tumor curettage and cancellous allogenic bone transplantation; 12 cases of tumor curettage, allograft massive cortical bone and cancellous bone transplantation; 2 cases of bone tumor segmental resection and allograft femoral shaft transplantation; 3 cases of bone tumor segmental resection and hemiarthrosis transplantation and 1 case of tumor excision and massive allograft sacrum transplantation. Results: 2 of 120 cases had minor rejection reaction only, who were mostly manifested as post-operative incision exudation, exudation was stopped and the incision was healed three months later, incision, and other cases are healed by the first intention. Conclusion: allograft bone has wide application scope, excellent effect and rare rejection reaction in bone tumour surgery. It is important in bone defect fillers. Currently, bone defect fillers are more and more. Common fillers include autogenous bone, allogeneic bone, artificial bone, artificial prosthesis, bone cement, etc. What is the position of allogeneic bone among various bone defect fillers? How about application scope, effect, rejection reaction, etc. in bone tumour surgery especially? In the paper, 120 cases of allogeneic bone transplantation in our department from October 1983 to March 2003 are summarized. The above issues are discussed.