Application of an Optosensing Chip Based on Molecularly Imprinted Polymer Coated Quantum Dots for the Highly Selective and Sensitive Determination of Sesamol in Sesame Oils

Abstract

A novel optosensing chip was constructed by anchoring the fluorescence sensing material layer based on molecularly imprinted polymer (MIP) coated CdSe/ZnS quantum dots (QDs) on a chip for highly selective and sensitive optosensing of sesamol in sesame oil. Many factors that affected the performance of the optosensing chip based on MIP-coated QDs are discussed. Under optimized conditions, the relative fluorescence intensity of the optosensing chip decreased linearly (r(2) > 0.99) with increasing sesamol concentration in the range from 2.4 × 10(-6) to 1.2 × 10(-3) mol L(-1) with a detection limit of 7.2 × 10(-8) mol L(-1). The relative standard deviation for five replicate detections of 4.8 × 10(-4) mol L(-1) sesamol was 2.2%. Recoveries of 94.8-102.3% were achieved by direct detection when the optosensing chip was used for the selective detection of sesamol in sesame oil. Practically, the optosensing approach showed high sensitivity, good selectivity, and excellent reproducibility for the detection of sesamol in real oil samples.

A Novel Tb@Sr-MOF as Self-Calibrating Luminescent Sensor for Nutritional Antioxidant

“…However, many disadvantages have various limitations such as time-consuming, cost, complicated preparation process, and the need for professionals. Therefore, it is exigent to explore a kind of simple, rapid, highly selective, and sensitive access for detecting sesamol [ 5 ].…”

Luminescent Molecularly Imprinted Polymers Based on Covalent Organic Frameworks and Quantum Dots with Strong Optical Response to Quinoxaline-2-Carboxylicacid

“…Luminescent covalent organic frameworks (COFs) with the porosity of COFs and intrinsic optical properties, which can transform the chemical signal produced by the host–guest interaction into detectable changes in luminescence, have attracted wide attention. Although various topological diagrams of building blocks with predesigned geometry and symmetry by virtue of dynamic covalent bonds have been developed for COFs synthesis [1,2,3,4,5], luminescent COFs remain a challenge. Most layered, two-dimensional COFs (2D-COFs) with uniform and perforated pores exhibit conjugated 2D layers and periodic columnar π–π arrays, which trigger the thermal decay of photoexcited states and result in less- or non-emissive luminescence [6].…”

“…Semiconductor quantum dots (QDs) are good inorganic chromophores with efficient size-dependent broadband absorption, high extinction coefficients, and intense size-tunable narrowband fluorescence. They have been widely used in bioanalysis [11], particularly because of their brightness and high stability with respect to photobleaching [1,3,12,13]. Optosensing via charge/energy transfer interactions with analytes have allowed QDs to become sensitive response elements.…”

Confined growth of CdSe quantum dots in colloidal mesoporous silica for multifunctional nanostructures

“…In order to enhance fluorescent response, decrease toxicity, and enable multi-functionalities, the quantum dots are frequently incorporated into a host matrix such as polymer or silica microspheres [7][8][9][10][11][12][13][14][15][16][17][18]. Among all the host materials, silica has been intensively investigated and broadly utilized, which is believed to benefit from its low reactivity, colloidal stability, biological compatibility and easy surface modification.…”