Application of ATC/DDD methodology to eveluate of antibiotic use in a general hospital in Turkey

Abstract

BackgroundThe aim of this study is to evaluate in-house antibiotic use in a state hospital in Turkey with its cost, using the ATC/DDD index, which is an accepted standard method.MethodsThis study was performed as a point prevalence study in a state hospital with 372 beds. All in-house patients using antibiotics on July 19, 2011 were included in the study. Indications for antibiotic use and information about the patients were recorded on special forms. Antibiotic use and cost analysis were evaluated using the ATC/DDD index, which is also suggested by the WHO to be used in similar studies.Findings147 patients out of 308 patients who were in-house were identified to use antibiotics with appropriate indications for prophylaxis or treatment in 61% of the patients. The rate of appropriate antibiotic use was identified to be in 78%, while this rate was 38.9% in surgical clinics. The daily cost of the antibiotics consumed on the date of the study was calculated as 4104.79 TL (=2476.80 USD).DiscussionThe rate of inappropriate use of antibiotics seems to be high in our hospital. This will result in both increased costs and also increased nosocomial infection rates with resistant species. Infectious disease specialists should take more active roles in the in-house antibiotic use, hospitals should prepare and implement their own principles of antibiotic use, and microbiology laboratories should be used more effectively. These measures would decrease the conspicuous shortcomings in the antibiotic use.

Antimicrobial consumption, costs and resistance patterns: a two year prospective study in a Romanian intensive care unit

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Relationship between Antimicrobial Consumption and the Incidence of Antimicrobial Resistance in Escherichia coli and Klebsiella pneumoniae Isolates

“…A study concluded that, DDD methods are useful for benchmarking purposes and do not imply the number of Days of Therapy (DOTs) or relative use for many antibacterial drugs [14]. Also, many studies demonstrated the use of DDD for measuring the Antibiotic consumption [12,[15][16][17][18].…”

ATC/DDD Method to Assess the Injectable Antibiotics Utilization in a Tertiary Care Teaching General Hospital in India

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