In the study of measures to improve channel efficiency, we developed and presented a performance analysis of a digital communication system for image transmission in a multipath channel with fading, in the MATLAB/Simulink environment, one of the main advan tages being that it provides high interference immunity in the presence of noise and interference and signal delays. The scheme has been investigated for bit error rate (BER) on additive white Gaussian noise (AWGN) channel and multipath Rice and Rayleigh fading channel operating under the influence of inter-symbol interference (hereinafter ISI) and different parameters for the channel, where we considered cases of signal delay similar for EPA (extended pedestrian a model (EPA) standards). In this paper, we estimate the effectiveness of compensation for signal distortion in radio channels with fading on the basis coded orthogonal frequency-division multiplexing (COFDM) technology, an adaptive equalizer, amplifiers on the transmitter side and a normalizer on t he receiver side, which is an acute problem in the field of wireless communication. This system can be applied to transmit better quality high-resolution radiological images over a wireless network inside a building and for a model analogous of pedestrian traffic.