Application of capillary electrophoresis‐mass spectrometry for determining organic food contaminants and residues

Abstract

Food contamination continues to be a serious problem around the world. Surveillance of chemical contaminants in foods is important not only for public health but also because of the negative economic impact of contamination. From the analytical perspective, analysis of contaminants in food is an extremely challenging area. There is a wide variety of questions, ranging from the quantification of extremely low levels of individual components to the detailed assessment and evaluation of the analytical technique possibilities. This review considers the applications of CE coupled to MS detection (CE-MS) for the analysis of organic contaminants in food. Analytical information on sample concentration techniques, as well as on the CE separation conditions and recoveries obtained from water and food are provided. Different sections include several fields of application, such as pesticides, drug residues, or toxic formed during food processing in different matrices. A number of tables report a comprehensive listing of CE-MS applications. As a result, this work presents an update overview on the principal application of CE-MS together with a discussion of their main advantages and drawbacks, and an outline of future trends on analysis of organic contaminants.

Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE‐MS

“…pesticides, pharmaceuticals, proteins and sugars). Despite the potential of the technique, the number of applications for determining food contaminants and residues is, so far, very limited (exceptions have been pesticides in fruits and vegetables [27][28][29][30][31] and veterinary drugs in animal products [26,[32][33][34][35]). …”

Sheath Liquids in CE-MS: Role, Parameters, and Optimization

“…Focusing on interfacing-and coupling-related parameters, several review papers include extensive tables listing separation-and detection-relevant data such as BGE composition and also SL composition and flow rates [22][23][24][25][26][27][28][29][30][31][32]. Browsing through these tables, several findings regarding SL composition can be deducted.…”

The application of CE‐MS in the trace analysis of environmental pollutants and food contaminants

“…Although these methods have been largely employed with satisfactory results there are disadvantages in the use of these procedures in that they are lengthy, laborious and consume large amounts of organic solvents. Trace enrichment by SPE and SPME are currently extraction techniques of choice [19,20]. The reader is also referred to a 2005 review on food analysis [45] by CE-MS, which included analysis of pollutants and other exogenous compounds in food samples.…”

“…Quite often, a trace enrichment step is necessary for clean-up of the sample and pre-concentration of the analytes in order to improve the quality of the analytical results obtained [19,20]. A single liquid-liquid extraction or a pre-concentration procedure such as SPE or solid-phase microextraction (SPME) is the most commonly used methods.…”