Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19

Li, Jiawei; Wang, Xiao; Huang, Xiao-Lu; Chen, Fangxing; Liu, Ying; Luo, Guangzuo; Xu, Xunhua

doi:10.1186/s12880-020-00456-5

Cited by 22 publications

(23 citation statements)

References 10 publications

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“…Our study on variations in CT utilization, protocols, and radiation doses demonstrates a lack of There are no specific recommended or target doses in patients with COVID-19 pneumonia, but when evaluation is limited to lung parenchyma, a CTDIvol <3mGy, as recommended for low dose chest CT for lung cancer screening may be sufficient for COVID-19 pneumonia [8]. There are studies on use of high-resolution and ultra-high-resolution chest CT in patients with COVID-19 pneumonia, most studies related to acquisition technique for scanning these patients describe use of non-contrast reduced-dose CT protocol [10,[19][20][21][22]. These studies describe use of high-pitch, selective photon shield with tin filter, low tube current and/or tube potential to obtain low-dose CT without loss of diagnostic information related to COVID-19 pneumonia [20].…”

Section: Discussionmentioning

confidence: 99%

Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study

et al. 2021

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Background There is lack of guidance on specific CT protocols for imaging patients with coronavirus disease 2019 (COVID-19) pneumonia. Purpose To assess international variations in CT utilization, protocols, and radiation doses in patients with COVID-19 pneumonia. Materials and Methods In this retrospective data collection study, the International Atomic Energy Agency (IAEA) coordinated a survey between May and July 2020 regarding CT utilization, protocols, and radiation doses from 62 healthcare sites in 34 countries across five continents for CT exams performed in COVID-19 pneumonia. The questionnaire obtained information on local prevalence, method of diagnosis, most frequent imaging, indications for CT, and specific policies on use of CT in COVID-19 pneumonia. Collected data included general information (patient age, weight, clinical indication), CT equipment (CT make and model, year of installation, number of detector rows), scan protocols (body region, scan phases, tube current and potential), and radiation dose descriptors (CT dose index (CTDI vol ) and dose length product (DLP)). Descriptive statistics and generalized estimating equations were performed. Results Data from 782 patients (median age (interquartile range) of 59(15) years) from 54 healthcare sites in 28 countries were evaluated. Less than one-half of the healthcare sites used CT for initial diagnosis of COVID-19 pneumonia and three-fourth used CT for assessing disease severity. CTDI vol varied based on CT vendors (7-11mGy, p<0.001), number of detector-rows (8-9mGy, p<0.001), year of CT installation (7-10mGy, p=0.006), and reconstruction techniques (7-10mGy, p=0.03). Multiphase chest CT exams performed in 20% of sites (11 of 54) were associated with higher DLP compared with single-phase chest CT exams performed in 80% (43 of 54 sites) (p=0.008). Conclusion CT use, scan protocols, and radiation doses in patients with COVID-19 pneumonia showed wide variation across healthcare sites within the same and different countries. Many patients were scanned multiple times and/or with multiphase CT scan protocols. See also the editorial by Lee .

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Section: Discussionmentioning

confidence: 99%

Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study

et al. 2021

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“…On the other hand, low-dose radiotherapy has been considered as one of the potential treatments for COVID-19 pneumonia. The results of the pilot trial evaluating low-dose whole-lung irradiation (LD-WLI) in patients with COVID-19 pneumonia show the feasibility of treatment in patients with moderate COVID-19 pneumonia [28][29][30][31].…”

Section: Discussionmentioning

confidence: 99%

“…This aspect must be considered for all patients with this new disease that is still so little known, especially in a follow-up to evaluate any outcomes [31].…”

Section: Discussionmentioning

confidence: 99%

Increased Radiation Dose Exposure in Thoracic Computed Tomography in Patients with Covid-19

et al. 2021

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The CT manifestation of COVID-19 patients is now well known and essentially reflects pathological changes in the lungs. Actually, there is insufficient knowledge on the long-term outcomes of this new disease, and several chest CTs might be necessary to evaluate the outcomes. The aim of this study is to evaluate the radiation dose for chest CT scans in COVID-19 patients compared to a cohort with pulmonary infectious diseases at the same time of the previous year to value if there is any modification of exposure dose. The analysis of our data shows an increase in the overall mean dose in COVID-19 patients compared with non-COVID-19 patients. In our results, the higher dose increase occurs in the younger age groups (+86% range 21–30 years and +67% range 31–40 years). Our results show that COVID-19 patients are exposed to a significantly higher dose of ionizing radiation than other patients without COVID infectious lung disease, and especially in younger age groups, although some authors have proposed the use of radiotherapy in these patients, which is yet to be validated. Our study has limitations: the use of one CT machine in a single institute and a limited number of patients.

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“…Li et al. reported 2.5-mGy CTDI vol for chest CT in COVID-19 patients with AEC and iterative reconstruction ( 18 ) . Hamper et al.…”

Section: Discussionmentioning

confidence: 99%

Chest Ct Usage in Covid-19 Pneumonia: Multicenter Study on Radiation Doses and Diagnostic Quality in Brazil

Bernardo¹,

Homayounieh²,

Cuter³

et al. 2021

Radiation Protection Dosimetry

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We assessed variations in chest CT usage, radiation dose and image quality in COVID-19 pneumonia. Our study included all chest CT exams performed in 533 patients from 6 healthcare sites from Brazil. We recorded patients’ age, gender and body weight and the information number of CT exams per patient, scan parameters and radiation doses (volume CT dose index—CTDIvol and dose length product—DLP). Six radiologists assessed all chest CT exams for the type of pulmonary findings and classified CT appearance of COVID-19 pneumonia as typical, indeterminate, atypical or negative. In addition, each CT was assessed for diagnostic quality (optimal or suboptimal) and presence of artefacts. Artefacts were frequent (367/841), often related to respiratory motion (344/367 chest CT exams with artefacts) and resulted in suboptimal evaluation in mid-to-lower lungs (176/344) or the entire lung (31/344). There were substantial differences in CT usage, patient weight, CTDIvol and DLP across the participating sites.

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Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19

Cited by 22 publications

References 10 publications

Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study

Variations in CT Utilization, Protocols, and Radiation Doses in COVID-19 Pneumonia: Results from 28 Countries in the IAEA Study

Increased Radiation Dose Exposure in Thoracic Computed Tomography in Patients with Covid-19

Chest Ct Usage in Covid-19 Pneumonia: Multicenter Study on Radiation Doses and Diagnostic Quality in Brazil

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