Application of CASIA SS-1000 Optical Coherence Tomography Tear Meniscus Imaging in Testing the Efficacy of New Strip Meniscometry in Dry Eye Diagnosis

Abstract

The SMTube was useful in DED diagnosis, the validity of which could be effectively evaluated by the CASIA SS-1000 AS-OCT TM parameters.

A novel strip meniscometry method for measuring aqueous tear volume in dogs: Clinical correlations with the Schirmer tear and phenol red thread tests

“…In human ophthalmology, the SMT may be useful for the diagnosis of dry eye disease in patients with different conditions, which includes an assessment of tear quality and the ocular surface state . Further research of dogs is needed that emphasize the relation between the SMT results and clinical signs.…”

“…The testing time of the SMT (5 seconds) is considerably shorter than that of the conventional STT. The clinical efficacy and correlations with other ocular surface examinations in the diagnosis of dry eye disease (or keratoconjunctivitis sicca) have been evaluated . In 2013, a commercial version of the SMT strip was produced and called the strip meniscometry tube (SMTube; Echo Electricity Co. Ltd., Tokyo, Japan).…”

“…Alternatively, in Canada and the United States, the SMTube is available with a different product name but has the same material and structure (i‐Tear Test; I‐MED Pharma Inc, Dollard‐Des Ormeaux, QC, Canada). Material and structural details of the SMTube can be found elsewhere, and we employed the SMTube for the SMT in the present study. Various other SMT applications beyond the diagnosis of dry eye disease have also been reported, such as time‐line measurements of tear volume and quick evaluation of treatment outcomes .…”

Diurnal variation of human tear meniscus volume measured with tear strip meniscometry self-examination

“…Diurnal variation has previously been examined using five optical coherence tomography measurements (from 9:00 to 21:00) [11] and using four Schirmer test measurements during hospitalization [12]. Tear strip meniscometry (SM) was recently introduced to be a non-invasive, fast, and simple test for measuring aqueous availability at the tear meniscus [13][14][15][16][17][18][19] (Fig 1). The structure and composition of meniscometry strips and the technique of SM have been described in detail previously [13,14].…”

“…SM was first described at 2006 and proven to have statistically significant linear correlation with the Schirmer test value, tear break-up time, corneal staining score, and tear meniscus height measurement by anterior optical coherence tomography [13,14]. The in vivo and in vitro reproducibility, sensitivity, and specificity were sufficiently evaluated [13] and SM has been used in many studies [14][15][16][17][18][19]. The purpose of this study was to capture diurnal variation of aqueous availability at the tear meniscus by measuring wetted length using SM through self-examination with seven measurements taken upon awakening to immediately before bedtime.…”