Application of Chemometric Techniques In The Evaluation of Bioactive Compounds and Antioxidant Activity of Fruit From Brazilian Cerrado

Guimarães, Ana Clara Garcia; Gomes, Marcos de Souza; Lima, Lidiany Mendonça Zacaroni; Sales, Priscila Ferreira de; Cunha, Mariana Crivelari da; Rodrigues, Luiz José; Barros, Hanna Elísia Araújo de; Pires, Caroline Roberta Freitas; Santos, Viviane Ferreira dos; Natarelli, Caio Vinícius Lima; Boas, Eduardo Valério de Barros Vilas

doi:10.1007/s11694-022-01736-0

Cited by 9 publications

(12 citation statements)

References 36 publications

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“…Regarding the quantification of phenolic compounds, Guimarães et al [ 15 ] observed that catechin (16.79 mg/100 g fw) and gallic acid (1.89 mg/100 g fw) were the major compounds in araticum pulp, followed by amounts lower than 0.55 mg/100 g fw for other phenolic acids (chlorogenic acid, caffeic acid, p -coumaric acid, ferulic acid, trans-cinnamic acid, m -coumaric acid, and o -coumaric acid) and flavonoids (quercetin, vanillin, and rutin). Besides that, Arruda et al [ 25 ] quantified 10 phenolic compounds, namely catechin (768.42 µg/g dw), epicatechin (661.81 µg/g dw), caffeic acid (124.31 µg/g dw), protocatechuic acid (97.92 µg/g dw), ferulic acid (53.71 µg/g dw), chlorogenic acid (43.45 µg/g dw), gentisic acid (14.00 µg/g dw), p -coumaric acid (11.86 µg/g dw), rutin (9.31 µg/g dw), and quercetin (7.80 µg/g dw), in araticum pulp.…”

Section: Bioactive Compounds Found In Araticum Fruit Partsmentioning

confidence: 99%

“…A series of studies have reported the antioxidant activity of several extracts and fractions obtained from the pulp [ 13 , 14 , 15 , 24 , 25 , 36 , 51 , 52 ], peel [ 16 , 17 , 18 , 23 , 24 , 25 ], and seeds [ 23 , 24 , 25 , 33 , 53 ] of araticum fruit through different in vitro antioxidant assays, including DPPH, TEAC, ORAC, FRAP, β-carotene/linoleic acid system, TBARS, phosphomolybdenum complex, and reducing power. As can be seen in Table 1 , phenolic compounds are the main bioactive compounds reported in these extracts/fractions from araticum fruit parts.…”

Section: Biological Activities Reported In Araticum Fruit Partsmentioning

confidence: 99%

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Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.)

Arruda

Borsoi

Andrade

et al. 2023

Plants

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Araticum (Annona crassiflora Mart.) is a native and endemic species to Brazilian Cerrado whose fruits have high sensorial, nutritional, bioactive, and economic potential. Its use in local folk medicine, associated with recent scientific findings, has attracted growing interest from different industrial sectors. Therefore, understanding the scientific advances achieved so far and identifying gaps to be filled is essential to direct future studies and transform accumulated knowledge into innovative technologies and products. In this review, we summarize the phytochemical composition, bioactivities, and food products from araticum fruit that have been reported in the scientific literature over the past 10 years. The compiled data showed that araticum fruit parts contain a wide range of bioactive compounds, particularly phenolic compounds, alkaloids, annonaceous acetogenins, carotenoids, phytosterols, and tocols. These phytochemicals contribute to different biological activities verified in araticum fruit extracts/fractions, including antioxidant, anti-inflammatory, anti-Alzheimer, anticancer, antidiabetic, anti-obesity, antidyslipidemic, antinociceptive, hepatoprotective, healing of the cutaneous wound, antibacterial, and insecticide effects. Despite the promising findings, further studies—particularly toxicological (especially, with byproducts), pre-clinical, and clinical trials—must be conducted to confirm these biological effects in humans and assure the safety and well-being of consumers.

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Section: Bioactive Compounds Found In Araticum Fruit Partsmentioning

confidence: 99%

Section: Biological Activities Reported In Araticum Fruit Partsmentioning

confidence: 99%

Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.)

Arruda

Borsoi

Andrade

et al. 2023

Plants

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“…Thus, the different extractor solvents used in the studies can, at least partially, explain the different values of total phenolic content found [ 31 ]. However, several studies used the same conditions to extract phenolic compounds from araticum pulp (successive extraction using 50% methanol and 70% acetone) and obtained discrepant results (total phenolic content values ranging from 2.22 to 10.08 mg GAE/g fw) [ 9 , 10 , 25 , 26 , 27 , 28 , 29 ]. Therefore, other factors such as geographical and environmental conditions of the fruit’s origin region (e.g., temperature, soil, incidence and intensity of light, harvest time, among others), physiological and genetic factors of the plant, and sample preparation and storage conditions may be associated with the observed variations in total phenolic values among studies [ 14 , 25 ].…”

Section: Resultsmentioning

confidence: 99%

“…Phenolic compounds are the most extensively documented group of secondary metabolites in the araticum pulp to date [ 8 , 9 , 11 , 14 , 25 ]. These compounds are characterized by having at least one aromatic ring with one or more hydroxyl substituent groups.…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, this fruit has been used for centuries in local and traditional medicine as a tonic and astringent and for the treatment of pain and rheumatism [ 6 ]. Recent studies have shown that araticum pulp exerts various bioactivities, including antioxidant [ 7 , 8 , 9 ], anti-inflammatory [ 10 ], antibacterial [ 11 , 12 ], anti-Alzheimer’s [ 13 ], and anticancer effects [ 14 ]. These effects have been attributed to the presence of different bioactive phytochemicals that can be found in araticum pulp.…”

Section: Introductionmentioning

confidence: 99%

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UHPLC-ESI-QTOF-MS/MS Profiling of Phytochemicals from Araticum Fruit (Annona crassiflora Mart.) and Its Antioxidant Activity

Arruda,

Angolini,

Eberlin

et al. 2023

Foods

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Araticum is a native species of the Brazilian Cerrado with a high potential for exploitation. Several studies have stated that araticum is a rich source of phytochemicals with multifaceted biological actions. However, little information is available regarding the characterization of phytochemicals found in the pulp of this fruit. In this context, this study aimed to carry out a comprehensive characterization of phytochemicals present in the araticum pulp using ultra-high-performance liquid chromatography coupled to a quadrupole time-of-flight mass spectrometer (UHPLC-ESI-QTOF-MS/MS). The antioxidant potential of araticum pulp was also evaluated. UHPLC-ESI-QTOF-MS/MS profiling of the phytochemicals allowed for the identification and annotation of 139 phytochemicals, including organic acids, jasmonates, iridoids, phenolic compounds, alkaloids, annonaceous acetogenins, fatty acid derivatives, and other compounds. Among them, 116 compounds have been found for the first time in araticum pulp. Phenolic compounds and their derivatives represented about 59% of the phytochemicals identified in the extract. Moreover, araticum pulp showed high total phenolic compound content and antioxidant activity. The majority of identified phytochemicals have been associated with key roles in the plant’s defense mechanisms against biotic and abiotic stress factors in the Cerrado environment. Furthermore, many of these phytochemicals found in the araticum pulp are already widely recognized for their beneficial effects on human health. Our findings showed that the araticum fruit contains different classes of phytochemicals that exert various biological activities, both in the plant itself and in humans.

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Araticum (Annona crassiflora Mart.): A critical review for the food industry

Fernandes Almeida,

Ferreira Moreno,

Paula Oliveira Machado

et al. 2024

Food Research International

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Application of Chemometric Techniques In The Evaluation of Bioactive Compounds and Antioxidant Activity of Fruit From Brazilian Cerrado

Cited by 9 publications

References 36 publications

Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.)

Scientific Advances in the Last Decade on the Recovery, Characterization, and Functionality of Bioactive Compounds from the Araticum Fruit (Annona crassiflora Mart.)

UHPLC-ESI-QTOF-MS/MS Profiling of Phytochemicals from Araticum Fruit (Annona crassiflora Mart.) and Its Antioxidant Activity

Araticum (Annona crassiflora Mart.): A critical review for the food industry

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