Application of Electrolyzed Hydrogen Water for Management of Chronic Kidney Disease and Dialysis Treatment—Perspective View

Abstract

Chronic kidney disease (CKD), which is globally on the rise, has become an urgent challenge from the perspective of public health, given its risk factors such as end-stage renal failure, cardiovascular diseases, and infections. The pathophysiology of CKD, including dialysis patients, is deeply associated with enhanced oxidative stress in both the kidneys and the entire body. Therefore, the introduction of a safe and widely applicable antioxidant therapy is expected as a measure against CKD. Electrolyzed hydrogen water (EHW) generated through the electrolysis of water has been confirmed to possess chemical antioxidant capabilities. In Japan, devices producing this water have become popular for household drinking water. In CKD model experiments conducted to date, drinking EHW has been shown to suppress the progression of kidney damage related to hypertension. Furthermore, clinical studies have reported that systemic oxidative stress in patients undergoing dialysis treatment using EHW is suppressed, leading to a reduction in the incidence of cardiovascular complications. In the future, considering EHW as one of the comprehensive measures against CKD holds significant importance. The medical utility of EHW is believed to be substantial, and further investigation is warranted.

Aquaphotomics Investigation of Electrolyzed Hydrogen Water: Understanding the Water Molecular Structure and Its Role in Scavenging Reactive Oxygen Species

“…However, the spotlight is increasingly turning towards emerging functional waters such as alkaline electrolyzed water, acidic electrolyzed water, electrolyzed hydrogen, hydrogen-enriched water, and tourmaline water. These waters are gaining attention not only for their potential health benefits but also because their distinctive properties arise from artificial treatments, not from the addition of substances with antioxidative properties [9,[11][12][13][14][15][16] Despite the increasing production and effectiveness of these newer options, the intricate mechanisms underlying their antioxidant and other health effects continue to be the subject of ongoing and intensive scientific exploration [9,[11][12][13]17]. Japan has emerged as a frontrunner in these initiatives; in 1993, the Japanese Society for Functional Water (JSFW) was established and serves as a national academic center dedicated to acquiring, accumulating, and disseminating accurate knowledge regarding functional water [18].…”