Application of essential oil as a sustained release preparation in food packaging

Ju, Jianting; Chen, Xueqi; Xie, Yunfei; Yu, Hang; Guo, Yahui; Cheng, Yuliang; Qian, He; Yao, Weirong

doi:10.1016/j.tifs.2019.08.005

Cited by 261 publications

(115 citation statements)

References 60 publications

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“…Hence, the interest in the research for novel alternatives to antibiotics has been growing. Natural products are becoming very promising as antimicrobial agents, being considered safe and environmentally friendly [9,10]. Antimicrobial peptides (AMPs) of natural origin have been the focus of great interest as alternatives to conventional antibiotics.…”

Section: Introductionmentioning

confidence: 99%

“…These consist of a complex mixture of chemical compounds, including terpenes, phenols, alcohols, aldehydes, ethers and ketones [20,21], most of which are hydrophobic or partially soluble in water. Usually, EOs have strong lipophilicity and volatility [9], making them suitable antibacterial agents for various applications encompassing anti-inflammatory and antioxidative properties. Nowadays, EOs application is found in many fields, including food preservation, cosmetics and biomedicine [22].…”

Section: Introductionmentioning

confidence: 99%

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Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria

et al. 2020

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The increased resistance of bacteria against conventional pharmaceutical solutions, the antibiotics, has raised serious health concerns. This has stimulated interest in the development of bio-based therapeutics with limited resistance, namely, essential oils (EOs) or antimicrobial peptides (AMPs). This study envisaged the evaluation of the antimicrobial efficacy of selected biomolecules, namely LL37, pexiganan, tea tree oil (TTO), cinnamon leaf oil (CLO) and niaouli oil (NO), against four bacteria commonly associated to nosocomial infections: Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa. The antibiotic vancomycin and silver nanoparticles (AgNPs) were used as control compounds for comparison purposes. The biomolecules were initially screened for their antibacterial efficacy using the agar-diffusion test, followed by the determination of minimal inhibitory concentrations (MICs), kill-time kinetics and the evaluation of the cell morphology upon 24 h exposure. All agents were effective against the selected bacteria. Interestingly, the AgNPs required a higher concentration (4000–1250 μg/mL) to induce the same effects as the AMPs (500–7.8 μg/mL) or EOs (365.2–19.7 μg/mL). Pexiganan and CLO were the most effective biomolecules, requiring lower concentrations to kill both Gram-positive and Gram-negative bacteria (62.5–7.8 μg/mL and 39.3–19.7 μg/mL, respectively), within a short period of time (averaging 2 h 15 min for all bacteria). Most biomolecules apparently disrupted the bacteria membrane stability due to the observed cell morphology deformation and by effecting on the intracellular space. AMPs were observed to induce morphological deformations and cellular content release, while EOs were seen to split and completely envelope bacteria. Data unraveled more of the potential of these new biomolecules as replacements for the conventional antibiotics and allowed us to take a step forward in the understanding of their mechanisms of action against infection-related bacteria.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria

et al. 2020

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“…In addition, the combination of nano-reinforced matrices with active antioxidant compounds could be considered a promising alternative for the controlled antioxidant release in active packaging films, prolonging the action time of the antioxidant packaging and improving the effect of the active substance in inhibiting food rancidity, extending shelf-life and controlling food safety [9]. A current increasing trend is the replacement of synthetic additives by the incorporation of active compounds coming from a natural origin into polymer matrices due to their lower toxicity and higher safety, providing antioxidant and/or antimicrobial properties to the active packaging systems [10,11].…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

et al. 2020

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In this study, new active PCL (poly(ε-caprolactone)) films containing α-tocopherol (TOC) and MSU-X mesoporous silica were prepared by melt blending. The studied additives were directly incorporated into the polymer matrix or by impregnating TOC into MSU-X silica (PCL-IMP). Thermal, optical, oxygen and water barrier properties as well as oxidation onset parameters, were studied. Films containing MSU-X and/or TOC showed a significant increase in oxidative onset temperature (OOT) and oxidative induction time (OIT), improving thermal stability against materials oxidation by the addition of mesoporous silica and TOC into the polymer matrix. In addition, the effect of MSU-X addition on the migration behaviour of α-tocopherol from active films was investigated at 40 °C using 50% (v/v) ethanol as fatty food simulant, showing PCL-IMP films the lower release content and diffusion coefficient (3.5 × 10−15 cm2 s−1). Moreover, radical scavenging (DPPH and ABTS) and antibacterial activity against E. coli and S. aureus were favoured by the release of α-tocopherol in the developed films. The obtained results have demonstrated the potential of the new PCL-based active formulations for TOC controlled release in antioxidant and antibacterial food packaging applications.

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“…Essential oils (EOs), due to their nature (as plant secondary metabolites), represents a safer alternative in many applications, such as food preservation, biomedicine, cosmetics, or agriculture [15]. From the chemical point of view, EOs represent a complex and unique mixture of compounds, specific for each plant and extraction procedure, including, but not limited to alkaloids, flavonoids, isoflavones, monoterpenes, phenolic acids, carotenoids, and aldehydes [16], strongly lipophilic and volatile and nearly insoluble in water.…”

Section: Introductionmentioning

confidence: 99%

The application of essential oils as a next-generation of pesticides: recent developments and future perspectives

Fierăscu

Fierascu

Dinu-Pîrvu

et al. 2019

Zeitschrift Für Naturforschung C

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Abstract The overuse of synthetic pesticide, a consequence of the rush to increase crop production, led to tremendous adverse effects, as they constitute a major pollutant for both soils and water, with a high toxicity towards humans and animals and, at the same time, led to development of pest resistance. In the last period, the researches were directed towards finding new solutions with a lower toxicity, less damaging behaviour towards the environment, and a better specificity of action. In this context, the use of essential oils, a complex and unique mixture of compounds, can be considered for the next-generation pesticides. This review aims to present the main applications of the essential oils as insecticides, herbicides, acaricides, and nematicides, as they emerged from the scientific literature published in the last 5 years (2015 to present). From the identified articles within the time period, only those dealing with essential oils obtained by the authors (not commercially available) were selected to be inserted in the review, characterized using established analytical techniques and employed for the envisaged applications. The review is concluded with a chapter containing the main conclusions of the literature study and the future perspectives, regarding the application of essential oils as next-generation pesticides.

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Application of essential oil as a sustained release preparation in food packaging

Cited by 261 publications

References 60 publications

Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria

Activity of Specialized Biomolecules against Gram-Positive and Gram-Negative Bacteria

Biodegradable Poly(ε-Caprolactone) Active Films Loaded with MSU-X Mesoporous Silica for the Release of α-Tocopherol

The application of essential oils as a next-generation of pesticides: recent developments and future perspectives

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