“…Recently, a number of materials have been designed to directly battle drug-resistant bacteria or enhance the antibiotic efficacy of existed antibiotics, such as gold nanoparticles, ruthenium complexes, cationic conjugated polymers, and antimicrobial peptides. − Carbon dots (CDs) have been an emerging nanomaterial in recent years that can be widely applied in bioimaging, biosensing, nanomedicine, drug delivery, cancer therapy, etc. − Moreover, some studies have revealed that CDs can function as an effective antibiotic, showing inhibitory effects on a broad spectrum. − These materials truly gain antimicrobial activities, but all of them are artificially synthesized through chemicals. On the other hand, we can always meet carbon nanoparticles in our everyday life, for example, automobile exhaust, cigarette smoke, chimney smoke, plant ash, and carbon black ink. − However, as far as we know, none of these studies referred to the relation between common daily carbon nanoparticles and antimicrobial activities, which is more important as such a worldwide issue influences every single human being.…”