Application of full scan gas chromatography high resolution mass spectrometry data to quantify targeted-pesticide residues and to screen for additional substances of concern in fresh-food commodities

Vargas-Pérez, Marta; Domínguez, Irene; González, Francisco Javier Egea; Frenich, Antonia Garrido

doi:10.1016/j.chroma.2020.461118

Cited by 17 publications

(4 citation statements)

References 18 publications

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“…However, this problem can be overcome by selecting characteristic ion fragments with lower abundance or sample dilution, which necessitate a second analysis. Vargas-Pérez and co-workers [35] proposed an application combining targeted and non-targeted approaches, using GC-Q-Orbitrap, for the multi-residue analysis of multiple pesticides in fruits and vegetables. The targeted method was successfully validated for 191 pesticides.…”

Section: Analysis Of Pesticidesmentioning

confidence: 99%

Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review

Gavage

Delahaut

Gillard

2021

Foods

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During the last decade, food, feed and environmental analysis using high-resolution mass spectrometry became increasingly popular. Recent accessibility and technological improvements of this system make it a potential tool for routine laboratory work. However, this kind of instrument is still often considered a research tool. The wide range of potential contaminants and residues that must be monitored, including pesticides, veterinary drugs and natural toxins, is steadily increasing. Thanks to full-scan analysis and the theoretically unlimited number of compounds that can be screened in a single analysis, high-resolution mass spectrometry is particularly well-suited for food, feed and water analysis. This review aims, through a series of relevant selected studies and developed methods dedicated to the different classes of contaminants and residues, to demonstrate that high-resolution mass spectrometry can reach detection levels in compliance with current legislation and is a versatile and appropriate tool for routine testing.

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Section: Analysis Of Pesticidesmentioning

confidence: 99%

Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review

Gavage

Delahaut

Gillard

2021

Foods

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“…Recent literature review shows that gas chromatography coupled to single or tandem mass spectrometric approaches (GC-MS, GC-MS/MS) served as an efficient tool for the determination of various organic compounds in food samples (Table 2). GC was used to quantify: 200 multiclass pesticides in fruits [67]; 14 lipophilic pesticides in raw propolis [68]; 5 organophosphorus pesticides (OPPs) in fruit juice and water [69], endocrine disrupting chemicals (EDCs) i.e., alkylphenols; 4 phenylphenols, bisphenol A; 7 parabens; 11 OPPs and triclosan in different cereal-based foodstuffs [70]; 4 isomers of hexachlorocyclohexane; 6 pyrethroid pesticides i.e., bifenthrin, fenpropathrin, cyhalothrin, cyfluthrin, cypermethrin, deltamethrin in milk [71]; 133 multiclass pesticides in pericarpium citri reticulatae (chenpi) [72]; 5 NSAIDs i.e., ibuprofen, paracetamol, diclofenac, naproxen, ketoprofen; 3 natural estrogens i.e., estrone, 17β-estradiol, estriol in Mussels Mytilus edulis trossulus [73], glyoxal and methylglyoxal in different alcoholic beverage and fermented foods [74], essential fatty acids in cereals and green vegetables [75], and fatty acids in grilled pork [76]. Crude fat, total saturated acids, and total trans fatty acids in home meal replacements, and restaurant foods were analyzed using GC-FID (gas chromatography-flame ionization detector).…”

Section: Gas Chromatography Gc In Analysis Of Selected Bioactive Compounds In Food Samplesmentioning

confidence: 99%

Current Strategies for Studying the Natural and Synthetic Bioactive Compounds in Food by Chromatographic Separation Techniques

2021

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The present study summarizes the new strategies including advanced equipment and validation parameters of liquid and gas chromatography methods i.e., thin-layer chromatography (TLC), column liquid chromatography (CLC), and gas chromatography (GC) suitable for the identification and quantitative determination of different natural and synthetic bioactive compounds present in food and food products, which play an important role in human health, within the period of 2019–2021 (January). Full characteristic of some of these procedures with their validation parameters is discussed in this work. The present review confirms the vital role of HPLC methodology in combination with different detection modes i.e., HPLC-UV, HPLC-DAD, HPLC-MS, and HPLC-MS/MS for the determination of natural and synthetic bioactive molecules for different purposes i.e., to characterize the chemical composition of food as well as in the multi-residue analysis of pesticides, NSAIDs, antibiotics, steroids, and others in food and food products.

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“…However, such differences do not prevent the observation of a high match for pesticide mass spectra, thus providing high confidence in compound identification (Figure 5). For example, non-targeted analysis of different food commodities-such as mushrooms and peppers, among others-by GC-EI-Q-Orbitrap-MS, along with further comparison of data against libraries containing more than 200,000 spectra, allowed the detection of several pesticides (i.e., lambda-cyhalothrin, triadimenol, imazalil, pyrimethanil, and tebuconazol as the most common compounds) without any prior hypothesis [169].…”

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confidence: 99%

Current Role of Mass Spectrometry in the Determination of Pesticide Residues in Food

Hernández‐Mesa

Moreno‐González

2022

Separations

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The extensive use of pesticides represents a risk to human health. Consequently, legal frameworks have been established to ensure food safety, including control programs for pesticide residues. In this context, the performance of analytical methods acquires special relevance. Such methods are expected to be able to determine the largest number of compounds at trace concentration levels in complex food matrices, which represents a great analytical challenge. Technical advances in mass spectrometry (MS) have led to the development of more efficient analytical methods for the determination of pesticides. This review provides an overview of current analytical strategies applied in pesticide analysis, with a special focus on MS methods. Current targeted MS methods allow the simultaneous determination of hundreds of pesticides, whereas non-targeted MS methods are now applicable to the identification of pesticide metabolites and transformation products. New trends in pesticide analysis are also presented, including approaches for the simultaneous determination of pesticide residues and other food contaminants (i.e., mega-methods), or the recent application of techniques such as ion mobility–mass spectrometry (IM–MS) for this purpose.

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Application of full scan gas chromatography high resolution mass spectrometry data to quantify targeted-pesticide residues and to screen for additional substances of concern in fresh-food commodities

Cited by 17 publications

References 18 publications

Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review

Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review

Current Strategies for Studying the Natural and Synthetic Bioactive Compounds in Food by Chromatographic Separation Techniques

Current Role of Mass Spectrometry in the Determination of Pesticide Residues in Food

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