Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry in Quality Control of Chinese Medicines

Cao, Jiliang; Jiang, Maoyuan; Hua, Shiyao; Yang, Lele; Li, Peng

doi:10.1007/978-981-99-9871-5_14

Quality Control of Chinese Medicines 2024

DOI: 10.1007/978-981-99-9871-5_14

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Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry in Quality Control of Chinese Medicines

Jiliang Cao,

Maoyuan Jiang,

Shiyao Hua

et al.

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2024

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Cited by 1 publication

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Comparison of Three Different Extraction Methods on Schizonepeta tenuifolia (Benth.) Briq Essential Oil: Chemical Constituents and in Vitro and in Silico Biological Activities

He,

Zhang,

Bai

2024

Chemistry & Biodiversity

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This study evaluated the effects of three extraction methods, hydrodistillation (HD), steam distillation (SD), and lipophilic solvent extraction (LSE), on the yield, chemical composition, and in vitro / in silico biological activities of Schizonepeta tenuifolia (Benth.) Briq essential oil (STEO). The highest yield of STEO was obtained by HD (0.750±0.040%), followed by SD (0.440±0.020%) and LSE (0.350±0.030%). Although their contents varied, menthone and pulegone predominated in HDEO, SDEO, and LSEO. HDEO displayed the strongest antioxidant ability, with a 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) IC50 value of 14.164±0.090 mg/mL and 2,2′‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulfonate) (ABTS) value of 0.326±0.023 mg/mL. SDEO demonstrated the highest antimicrobial activity against Staphylococcus aureus and Escherichia coli and HDEO the highest potent anti‐inflammatory activity. The molecular docking of menthone and pulegone demonstrated strong binding to inflammatory targets, including prostaglandin‐endoperoxide synthase 1 (PTGS1) and 2 (PTGS2) and tumor necrosis factor alpha (TNF‐α). In short, the extraction method significantly affected the yield, composition, and biological activity of STEO.

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Comparison of Three Different Extraction Methods on Schizonepeta tenuifolia (Benth.) Briq Essential Oil: Chemical Constituents and in Vitro and in Silico Biological Activities

He,

Zhang,

Bai

2024

Chemistry & Biodiversity

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Application of Gas Chromatography and Gas Chromatography–Mass Spectrometry in Quality Control of Chinese Medicines

Cited by 1 publication

References 97 publications

Comparison of Three Different Extraction Methods on Schizonepeta tenuifolia (Benth.) Briq Essential Oil: Chemical Constituents and in Vitro and in Silico Biological Activities

Comparison of Three Different Extraction Methods on Schizonepeta tenuifolia (Benth.) Briq Essential Oil: Chemical Constituents and in Vitro and in Silico Biological Activities

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