Application of gas chromatography–tandem mass spectrometry to the analysis of pesticides in fruits and vegetables

Vidal, José Luis Martı́nez; Arrebola, Francisco; Mateu-Sánchez, M.

doi:10.1016/s0021-9673(02)00444-2

Cited by 80 publications

(11 citation statements)

References 23 publications

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“…The LC‐MS/MS described in this work is simple (no cleanup procedure), fast and allows the simultaneous determination of a higher number of compounds (44) than the previously published methods in watermelons 44–48.…”

Section: Resultsmentioning

confidence: 99%

Residue analysis of multi‐class pesticides in watermelon by LC‐MS/MS

Park

Lee

Kim

et al. 2010

J of Separation Science

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As watermelon is farmed primarily by protected and successive cultivation techniques, a number of pesticides are required for the control of pests and diseases. To evaluate the harmful effects of pesticides in watermelon and to guarantee consumers' safety, a rapid screening process for pesticides is required. A LC-MS/MS method was applied for the direct quantitation of 44 pesticide residues in watermelon. A Zorbax XDB-C(18) column was selected for analysis, with a mobile phase consisting of a gradient system of water and 5 mM methanolic ammonium formate. MS/MS experiments were performed in ESI positive ion and multiple reaction monitoring modes. The LOQs were in the range of 1-26 microg/kg, thereby indicating good sensitivity. Most of the recoveries ranged between 70-131% with RSDs < or = 20%. We suggested that the amount of pesticide residues such as pyroquilon (pyn), boscalid (bd), and dimethomorph (di) in amides (AM) and cinosulfuron (ci) in ureas (UR) may have been overestimated for the pesticides owing to increased alpha-error risk, whereas the amounts of pesticide residues, such as imibenconazole (ie) in the triazoles (TR) and fenpyroximate (fee) in the imidazoles (IM), may have been underestimated as the result of increased beta-error risk. The current method allowed for the rapid quantitation and identification of low pesticide levels in the watermelon samples. No pesticide residues were detected in any of the surveyed watermelons obtained from eight local markets in the Republic of Korea. Statistical analysis of the recoveries classified the 44 pesticides into nine groups and three overall categories.

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Section: Resultsmentioning

confidence: 99%

Residue analysis of multi‐class pesticides in watermelon by LC‐MS/MS

Park

Lee

Kim

et al. 2010

J of Separation Science

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“…According to a review by the US Geological Survey National Water Quality Laboratory (USGS),2, 3 the standard routine analysis for trace pesticide residue is based mainly on gas chromatography (GC) with flame photometric detection offering an excellent limit of detection (LOD) down to sub‐parts‐per‐million. The advantage of using GC arises from its high separation power and, in addition, sensitivity and/or selectivity can be achieved through a selection of detectors such as electron capture detector (ECD),4 nitrogen–phosphorus detector (NPD),5 and mass spectrometry (MS) 6, 7. Liquid chromatography coupled to MS (LC–MS) has also been demonstrated in recent years to be a potential technique particularly for determination of pesticides of low volatility and thermolability 8, 9.…”

Section: Introductionmentioning

confidence: 99%

Surface‐enhanced Raman spectroscopic analysis of fonofos pesticide adsorbed on silver and gold nanoparticles

Vongsvivut

Robertson

McNaughton

2010

J Raman Spectroscopy

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Surface-enhanced Raman scattering (SERS) spectra of fonofos, an organophosphorous pesticide (OPP), were recorded using citrate-reduced silver (Ag) and gold (Au) colloidal nanoparticles in the form of dried films. In this study, significant enhancements were achieved with fonofos concentrations down to ∼10 ppm with the Ag colloids, demonstrating a potential for the technique in the analysis of fonofos residues. Successful formation of the SERS-active metal aggregates was indicated by the presence of a plasmon band at longer wavelengths in the UV-visible spectrum. Transmission electron microscopy (TEM) images revealed distinctively different morphologies of the aggregates formed by the two metals, while the observed SERS spectral features of fonofos were also found to be different for molecules adsorbed on Ag and Au colloidal surfaces. This evidence suggests metal-induced changes in adsorption behavior of the fonofos analyte, leading to the different binding structures onto the different metal surfaces. Comparisons between the most prominent SERS-enhanced bands and the precise mode descriptions predicted through density functional theory (DFT) simulations at the B3LYP/6-311+G(d,p) level allowed an in-depth orientation analysis of the adsorbed species on metal surfaces. Nevertheless, the ring vibrations were found to possess a major contribution in the observed SERS enhancements for both metal nanoparticles.

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“…In recent years, gas chromatography (GC), gas chromatography–mass spectrometry (GC‐MS), gas chromatography–ion trap mass spectrometry (GC‐ITMS; Tao et al ., ) and gas chromatography–tandem mass spectrometry (GC‐MS/MS; Martínez Vidal et al ., ) have made much progress in the field of monitoring pesticides because of the high separation power, selectivity and identification capabilities of MS. However, GC‐MS/MS, and GC‐ITMS are very expensive.…”

Section: Introductionmentioning

confidence: 99%

A QuEChERS‐based extraction method for the residual analysis of pyraclofos and tebufenpyrad in perilla leaves using gas chromatography: application to dissipation pattern

Mahmud

Rahman

et al. 2012

Biomedical Chromatography

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The objective of this work was to establish a simple extraction method for the residual analysis of pyraclofos and tebufenpyrad in Perilla leaves. A QuEChERS (quick, easy, cheap, effective, rugged and safe) method was used for extraction using ethyl acetate as an extraction solvent, and cleanup was carried out using dispersive solid‐phase extraction technique. The samples were analyzed using gas chromatography with nitrogen phosphorous detector and confirmed by gas chromatography–mass spectrometry. The linearity was excellent (r2 = 1.0) in matrix‐matched calibration for both pesticides. The recoveries at two fortification levels were 80.76–95.38% with relative standard deviation lower than 5%. The limits of detection and limits of quantification were 0.01 and 0.033 mg/kg for both pesticides, respectively. The results revealed that the dissipation pattern of pyraclofos and tebufenpyrad followed first‐order kinetics. The pyraclofos and tebufenpyrad residues declined to a level below the maximum residue limits within 14 day between the last application and harvesting. We suggest that pyraclofos and tebufenpyrad could be used efficiently on perilla leaves under the recommended dosage conditions. Copyright © 2012 John Wiley & Sons, Ltd.

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Application of gas chromatography–tandem mass spectrometry to the analysis of pesticides in fruits and vegetables

Cited by 80 publications

References 23 publications

Residue analysis of multi‐class pesticides in watermelon by LC‐MS/MS

Residue analysis of multi‐class pesticides in watermelon by LC‐MS/MS

Surface‐enhanced Raman spectroscopic analysis of fonofos pesticide adsorbed on silver and gold nanoparticles

A QuEChERS‐based extraction method for the residual analysis of pyraclofos and tebufenpyrad in perilla leaves using gas chromatography: application to dissipation pattern

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