Application of Glass Reinforced Hydroxyapatite Composite in the Treatment of Human Intrabony Periodontal Angular Defects – Two Case Reports

Abstract

Bony defects caused by periodontitis are often treated by regenerative therapy using autografts and/or allografts. Alloplasts such as hydroxyapatite or ceramics and bioactive glasses are used as osteoconductive materials that serve as scaffold for new bony ingrowth. The purpose of this study was to ascertain the possible regenerative capability of glass reinforced hydroxyapatite (Bonelike¬)¬¬¬ an osteoconductive synthetic graft in the treatment of human periodontal intrabony angular defects. The material was placed in 2 defects in 2 individual patients and clinical parameters such as probing depth (PD) and clinical attachment level (CAL) have been included. Bone fill was determined using an intra oral periapical radiograph (IOPA) and Autocad Software. After 3 months implantation period, there was an improvement in CAL and reduction in PD along with bone fill was observed.

Hydroxyapatite and tricalcium phosphate composites with bioactive glass as second phase: State of the art and current applications

“…Such composite is reported to stimulate new bone formation more quickly than commercial HA, in particular during early periods of implantation . Bonelike ® grafts in particulated form have been also successfully employed in several clinical applications, namely in maxillofacial and oral surgery, orthopaedics, and implantology . Radiological and histological investigations demonstrated that such composite is highly bioactive, it is rapidly osteointegrated after implantation and it resorbs at a rate that is compatible with the new bone formation.…”