Applications of Immunocytochemistry 2012
DOI: 10.5772/34058
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Application of Immunocytochemistry to Sputum Cells to Investigate Molecular Mechanisms of Airway Inflammation

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“…The irritants from the tobacco reduce the function of the anti-protease proteins otherwise known as alpha antitrypsin that serves as a protection from oxidative stress. [6,7]. This causes an increase in the inflammatory proteolytic enzymes that destroy the alveoli.…”
Section: Introductionmentioning
confidence: 99%
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“…The irritants from the tobacco reduce the function of the anti-protease proteins otherwise known as alpha antitrypsin that serves as a protection from oxidative stress. [6,7]. This causes an increase in the inflammatory proteolytic enzymes that destroy the alveoli.…”
Section: Introductionmentioning
confidence: 99%
“…This causes an increase in the inflammatory proteolytic enzymes that destroy the alveoli. This destruction causes an irreversible inhibition of recoiling that limits gas exchange [7]. Therefore, carbon dioxide retention occurs and patients become hypoxic and hypercapnic.…”
Section: Introductionmentioning
confidence: 99%