Application of Magnetic Iron Oxide Nanostructures in Drug Delivery: A Compact Review

Omoruyi, Inono C.; Omoruyi, Jeffery I.; Aghedo, Oscar N.; Archibong, Ukeme D.; Ifijen, Ikhazuagbe H.

doi:10.1007/978-3-031-22524-6_22

Cited by 8 publications

(1 citation statement)

References 41 publications

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“…Additionally, NMs can reach every organ and system through the bloodstream due to their small size [1,[7][8].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs

Ifijen,

Omonmhenleb

2023

Alger. j. biosciences

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The impact of exposing significant mouse organs to cerium oxide nanoparticles (CeO2 NPs) has received considerable attention in the literature, but a comprehensive review on this topic is lacking. This review aims to address this gap by examining the influence of CeO2 NPs on the release rate of reactive oxygen species (ROS) in various organs of mice. CeO2 NPs have demonstrated potential therapeutic applications due to their ROS-scavenging abilities, which are relevant to oxidative stress-related diseases. Recent studies investigating the effect of CeO2 NPs on ROS release rate in organs such as the liver, spleen, lung, and brain are highlighted in this article. The findings reveal a complex interaction between CeO2 NPs and the ROS system, influenced by factors such as particle dose, size, and surface chemistry. Furthermore, the impact of CeO2 NPs on ROS release rate is organ-specific and dependent on the tissue microenvironment. The review also addresses the potential toxicity of CeO2 NPs and emphasizes the need for further research to better comprehend their mechanisms of action and long-term effects. By providing valuable insights into the influence of CeO2 NPs on ROS release rate in mice organs, this review holds significant implications for the therapeutic applications of CeO2 NPs in oxidative stress-related diseases. This review contributes to the existing body of knowledge by examining the impact of CeO2 NPs on ROS release rate in various mouse organs

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“…Additionally, NMs can reach every organ and system through the bloodstream due to their small size [1,[7][8].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs

Ifijen,

Omonmhenleb

2023

Alger. j. biosciences

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Challenges and Future Perspectives of Biomimetic Materials for Biomedical Applications: Bridging the Gap Between Nature and Medicine

Ighodaro,

Osarobo,

Onuguh

et al. 2024

The Minerals, Metals &Amp; Materials Series

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Treatments of Mycobacterium tuberculosis and Toxoplasma gondii with Selenium Nanoparticles

Ifijen

Atoe²,

Ekun

et al. 2023

BioNanoSci.

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Toxoplasma gondii and Mycobacterium tuberculosis are pathogens that are harmful to humans. When these diseases interact in humans, the result is typically fatal to the public health. Several investigations on the relationship between M. tuberculosis and T. gondii infections have found that there is a strong correlation between them with each infection having a reciprocal effect on the other. TB may contribute to the reactivation of innate toxoplasmosis or enhance susceptibility to a new infection, and toxoplasma co-infection may worsen the severity of pulmonary tuberculosis. As a consequence, there is an earnest and urgent necessity to generate novel therapeutics that can subdue these challenges. Selenium nanostructures’ compelling properties have been shown to be a successful treatment for Mycobacterium TB and Toxoplasma gondii. Despite the fact that selenium (Se) offers many health advantages for people, it also has a narrow therapeutic window; therefore, consuming too much of either inorganic or organic compounds based on selenium can be hazardous. Compared to both inorganic and organic Se, Se nanoparticles (SeNPs) are less hazardous. They are biocompatible and excellent in selectively targeting specific cells. As a consequence, this review conducted a summary of the efficacy of biogenic Se NPs in the treatment of tuberculosis (TB) and toxoplasmosis. Mycobacterium tuberculosis , Toxoplasma gondii , and their co-infection were all briefly described.

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Application of Magnetic Iron Oxide Nanostructures in Drug Delivery: A Compact Review

Cited by 8 publications

References 41 publications

The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs

The Impact of Cerium Oxide Nanoparticles on Reactive Oxygen Species (ROS) Release Rate in Mice Organs

Challenges and Future Perspectives of Biomimetic Materials for Biomedical Applications: Bridging the Gap Between Nature and Medicine

Treatments of Mycobacterium tuberculosis and Toxoplasma gondii with Selenium Nanoparticles

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