Application of model of incremental haemodialysis, based on residual renal function, at the initiation of renal replacement therapy

Incremental Versus Conventional Hemodialysis for Preservation of Residual Kidney Function in Patients on Regular Hemodialysis

“…In patients who began 2-and 3 HD / week, the GFR range was 2-12, 6 mL / min and 0, 2-13, 6 mL / min, respectively. 8 We found marked increase in hemoglobin in incremental group; compared to conventional group; during the serial measurements (p < 0.05), which came in agreement with Merino et al 11 and A. Mathew et al 7 Hemoglobin and hematocrit enhanced after 1 year and the mean dose of erythropoiesis stimulating factors (ESF) did not raise significantly, reported by Merino et al 2017, which was darbepoetin (mcg / week), 27 ± 21 and 30 ± 22 mcg / week, p = 0.725 in our case. 11 Liu et alreported thatthose on incremental HD appeared to be female and thinner relative to patients on traditional HD.…”

“…9 A. Mathew et al reported that, no statistical disparity with all-cause mortality in subgroups of age , gender , ethnicity, central venous catheter use or diabetes condition in preset subgroup analyses of the matched cohort compared incremental HD to conventional HD. 7 We found marked increase in UOP in incremental group; compared to conventional group; during the serial measurements (p < 0.05), which came in agreement with Liu et al 9 , A. Mathew et al 7 , Lucas et al 8 ,A. T. Mathew et al 10 and Merino et al 11 Liu et alreported that those on incremental HD appeared to be female and thinner relative to those on traditional HD. The amount of urine in the incremental HD group was higher relative to the conventional HD group 9.…”

“…Regarding Outcome data, (20%) of patients had hypotension, (15%) had hospital admission, while nobody suffered mortality, which came in agreement with Lucas et al 8 Lucas et al reported thatin the 2-and 3-HD / week groups, hospitalization period was 4 (0-15) and 11 (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) days/patient-years, respectively (median and IQR, = 0, 068). 8 No substantial difference in the comparative study between the 2 groups with respect to all basic clinical data (p > 0.05) , which came in agreement with A. Mathew et al 7 , Lucas et al 8 and Liu et al .…”

End-Stage Kidney Patients Require Hemodialysis Therapy Full Start

“…After 24 months, 35% of them were still on twice-weekly HD. In a group of 30 incident patients on twice-weekly, Merino et al [62] have reported that 50% of the patients were switched to thrice-weekly HD before 1 year. In another retrospective study from the University of California Irvine, 8 out of 13 (62%) patients needed to be switched to thriceweekly HD in an average of 8 months.…”

Dialisi incrementale: una procedura differente dalla dialisi infrequente

“…Kalantar-Zadek et al 33 suggeriscono che probabilmente 13.000 pazienti veterani in dialisi avrebbero potuto iniziare con una dialisi bisettimanale, definita incrementale, che avrebbe prodotto anche un notevole risparmio sui costi dell’assistenza sanitaria statunitense; tutto questo adducendo una poco convincente valutazione retrospettiva su una migliore qualità di vita rispetto ai centri per pazienti non veterani. Altri autori californiani propongono, definendola INC, per un follow-up di 2 anni, la dialisi bisettimanale 34 ; così anche il gruppo spagnolo di Merino et al 35 Da segnalare l’esperienza di Oby et al 36 di confronto tra dialisi convenzionale e dialisi definita incrementale ma ben chiaramente tutti pazienti erano trattati in ritmo bisettimanale. Dopo pochi mesi un’altra osservazione è stata fatta dallo stesso gruppo americano comparando due coorti di pazienti statisticamente troppo sbilanciare sulla sopravvivenza di 50.163 pazienti in dialisi convenzionale versus 434 pazienti in dialisi definita incrementale.…”