As the construction of mountainous highways continues to heat up, the stability analysis of road graben slopes becomes one of the current research hotspots. In this paper, based on the saturated-unsaturated seepage theory, the force analysis of the road graben slope under rainfall conditions and its laws are studied. Firstly, the damage mode of the road graben slope and its three damage stages of creeping deformation, sliding damage and tendency to stability are summarized according to the engineering practice and literature survey, and the right side of the road graben slope from K316+439 to K316+859 of Longlian Expressway is monitored, so as to amend the next theoretical analysis. The three stages of rainfall infiltration were analyzed, the state variables and material variables of soil water were selected according to the continuous medium theory and the soil water suction analysis was carried out. Based on the saturated-unsaturated seepage theory, the fluid-structure interaction mathematical model and soil moisture characteristic curve (SWCC) model under rainfall infiltration conditions were established, and the stress of the cutting slope under saturation conditions was analyzed. The experimental results show that for the soil at the foot of the slope, the infiltration depth of rainfall is limited due to the low permeability coefficient, and the change of seepage field is not obvious; the longer the rainfall is held, the deeper the infiltration depth is, and the rainfall will continuously replenish the groundwater, so the force on the slope of the road graben will increase continuously and finally reach the limit of damage. When the rainfall intensity is 5mm-h-1, the decline of stability coefficient for 48 h is 0.121; the initial stability coefficient of the slope is the largest when the dip angle of the weak interlayer is equal to 25∘, and the stability coefficient decreases rapidly with the rainfall time, and when the rainfall reaches 60 h, the stability coefficient tends to be stable and the equilibrium of the slope force no longer changes.