Application of Niosomes in Cosmetics: A Systematic Review

Abstract

A rising volume of the literature acknowledges the significance of nanotechnology in the cosmetics industry, particularly with the invention and use of techniques based on niosomes to generate unique formulations with both medicinal and aesthetic benefits. The current study’s objectives are to undertake a comprehensive review of the previously published data on the use and applications of niosomes in cosmetics and to give a succinct summary of that data. Preferred Reporting standards for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used in the design of the current review. The core concept and keywords were derived from the research question using the SPIDER tool. The main steps of this review included: design of the research question, preliminary research, search strategy, searching the database, exclusion and inclusion criteria, approval by authors, title and abstract screening, reporting of the number of data selected, full text download and reading, manual research (Google Scholar, Scopus, and WoS), data extraction and quality assessment, double data checking, and manuscript writing, revision, and submission. After thorough data analysis, it was discovered that a cosmetic product’s aesthetic impact significantly improved when it was created utilising niosomes technology. The majority of cosmeceutical niosomes’ skin and hair products demonstrated an enhanced therapeutic and cosmeceutical effect. These discoveries may contribute to the treatment of skin conditions under the umbrella of cosmeceutical niosomes.

Niosomes: Composition, Formulation Techniques, and Recent Progress as Delivery Systems in Cancer Therapy

“…The therapeutic effectiveness and delivery of functionalized nanoparticles have several benefits, such as increased drug solubility, encapsulation efficiency, and improved pharmacokinetic profile of bioactive molecules [ 93 , 94 ]. By using niosomes and other nanoparticles, a variety of bioactive molecules can be loaded, leading to efficient targeted medication administration and improved physico-chemical stability of cosmeceutical and pharmaceutical products ( Table 2 ) [ 19 , 95 ].…”

“…Given the immense potential in delivery systems, there is a growing interest in comparing the benefits of niosomes entrapment with those of liposomes. However, only a few studies have moved toward pre-clinical and clinical trials, most being focused on topical delivery in the cosmetic field because, compared to liposomes, niosome formulations have showed superior skin permeation potential and higher stability [ 18 , 19 , 20 ].…”

Unravelling the Absence of Testosterone Peak in Niosomes Using DSC; Insights from FTIR and HRTEM Investigations

“…Niosomes are a type of lipidbased vesicle that has been extensively studied for their potential as drug carriers. They offer numerous advantages over traditional drug delivery systems, such as increased stability, biocompatibility, and improved bioavailability [3]. The composition and properties of niosomes can signi cantly in uence their e cacy as drug carriers.…”

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“…Thanks to their composition, niosomes are biodegradable and biocompatible, on account of the similarity between the lipids used for niosome production and the ones found in the human body, especially on the cellular membranes [41,42]. Additionally, when compared to their ancestors, liposomes, niosomes possess higher stability and longer shelf-life, a better capacity for controlled drug release, and lead to higher drug bioavailability [43]. The use of nanotechnology for drug delivery can not only protect the drug chemical and metabolic degradation, but also allow increased permeation thro biological barriers, and enable a controlled, sustained, and targeted drug delivery, h leading to more localized therapeutic effects, and thus reduced systemic toxicity [31 Several types of nanosystems have been developed over the years, na nanoemulsions, micelles, polymeric nanoparticles, and lipid nanoparticles, suc liposomes, and their more recent and innovative alternatives, ethosomes, transferso and niosomes [34][35][36].…”

“…Thanks to their composition, niosomes are biodegradable biocompatible, on account of the similarity between the lipids used for nios production and the ones found in the human body, especially on the cellular membr [41,42]. Additionally, when compared to their ancestors, liposomes, niosomes po higher stability and longer shelf-life, a better capacity for controlled drug release, and to higher drug bioavailability [43].…”