Application of Orthogonal Design to Optimize Extraction of Polysaccharide from &lt;i&gt;Cynomorium songaricum&lt;/i&gt; Rupr (Cynomoriaceae)

Wang, X; Wang, F; Jing, Yongshuai; Wang, Y; Lin, Pingzhou; Yang, Lu

doi:10.4314/tjpr.v14i7.8

Cited by 2 publications

(2 citation statements)

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“…Polysaccharide extraction methods, including the use of acid or enzyme-based extraction, microwave or ultrasound-assisted, and ultra-high pressure-based approaches, have been developed, based on traditional aqueous extraction [10,[67][68][69][70][71][72][73][74].…”

Section: 2therapeutic Methodsmentioning

confidence: 99%

Polysaccharides from Chinese herbs as natural weapons against colorectal cancer

et al. 2023

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Colorectal cancer (CRC) ranks third and second among the most widespread cancers worldwide and the most common causes of human death due to cancer, respectively. Further, for unknown reasons, numbers of young patients diagnosed with colon cancer has increased. Polysaccharides are important functional phytochemicals reported to have anti-CRC effects. Moreover, CRC development and progression is closely related to the gut microbiome. Although approaches for treating CRC have been the subject of some review papers, research into traditional Chinese medicine (TCM) treatments for CRC and the underlying mechanisms involving polysaccharides have not been reviewed. Here, we reviewed the mechanisms underlying treatment of CRC using TCM polysaccharides, based on the etiology of CRC, and common treatment methods applied. The relationship between intestinal microbes and CRC, the mechanism by which TCM polysaccharides induce CRC cell apoptosis, and how TCM polysaccharides promote immune responses are discussed, as well as TCM polysaccharide use in combination with chemotherapy. TCM polysaccharides provide options for CRC treatment, due to their advantages of having multiple targets, eliciting modest adverse reactions, and wide range of available sources.

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Section: 2therapeutic Methodsmentioning

confidence: 99%

Polysaccharides from Chinese herbs as natural weapons against colorectal cancer

et al. 2023

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“…On this basis, the single factor method can be used to test the factors that have the greatest influence on the extraction rate of polysaccharides, and then the orthogonal test method is used to test the three factors with the greatest influence in the early stage, and the extraction process conditions with the best yield of maidenhairtree polysaccharides are determined [14] , which provides a theoretical reference for further research and development of maidenhairtree polysaccharides in the future.…”

Section: Preparation Of Maidenhairtree Polysaccharidesmentioning

confidence: 99%