Application of Oxygen Reduction Reaction, Oxygen Evolution Reaction and Hydrogen Evolution Reaction in Electrochemical Biosensing

Abstract

Signal amplification based on catalytic reactions is one of the effective strategies to improve the sensitivity of electrochemical biosensors in which additional chemicals as the substrates are acquired. Water and oxygen are two simple and natural small molecules existed in the reaction medium of electrochemical biosensors. In this work, we reviewed the progress in the design of electrochemical biosensors with water or oxygen as the reaction substrate by oxygen reduction reaction (ORR), oxygen evolution reaction (OER) or hydrogen evolution reaction (HER) for signal enhancement.