Application of Polyethylene Glycolic Acid Felt with Fibrin Sealant to Prevent Postoperative Pancreatic Fistula in Pancreatic Surgery

Abstract

In summary, our procedure using PGA felt with fibrin sealant may reduce the risk of severe POPF.

Distal Pancreatectomy Utilizing a Flexible Stapler Closure Eliminates the Risk of Pancreas-Related Factors for Postoperative Pancreatic Fistula

“…They include artificial patches [32], glue applications [21,33], pancreatico-jejunostomies [16,27,28], extra-pancreatic organ patches [16,34,35], and octreotide [36]. Despite these attempts, the occurrence of PF has continued to vex surgeons.…”

Soft coagulation, polyglycolic acid felt, and fibrin glue for prevention of pancreatic fistula after distal pancreatectomy

“…5,6 Polyethylene glycolic acid (PGA) felt is a soft and fl exible absorbable nonwoven textile, and is widely used for tissue reinforcement. [7][8][9] Its attachment on a tissue is greatest when applied in combination with fi brin glue. We herein report the impact of using soft coagulation followed by the application of PGA felt and fi brin glue to prevent PF after DP.…”

Optimal stapler cartridge selection according to the thickness of the pancreas in distal pancreatectomy

“…In previous studies, BMI, [6,7,10] thickness, [7,8] and texture [8,11] have been identified as risk factors for POPF after DP. Various efforts to reduce the POPF rate have been attempted, including perioperative treatment with octreotide analog, pasireotide, [12] polyethylene glycolic acid mesh, [13] topical absorbable fibrin sealant patch, [14] pancreaticojejunostomy, [15] falciform ligament patch, [16] prolonged prefiring compression, [17] and seromuscular patch. [18] The method of pancreas stump closure is a major factor in preventing POPF.…”