Handbook of Polymers for Pharmaceutical Technologies 2015
DOI: 10.1002/9781119041375.ch2
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Application of Polymer Combinations in Extended Release Hydrophilic Matrices

Abstract: DESCRIPTIONPolymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of… Show more

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Cited by 6 publications
(5 citation statements)
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“…In addition, the degree of substitution by the methoxy group showed a rational correlation to the hydrophobicity and the rate of hydration. Accordingly, methylcellulose products that had higher degrees of substitution were water insoluble …”
Section: Resultsmentioning
confidence: 99%
“…In addition, the degree of substitution by the methoxy group showed a rational correlation to the hydrophobicity and the rate of hydration. Accordingly, methylcellulose products that had higher degrees of substitution were water insoluble …”
Section: Resultsmentioning
confidence: 99%
“…Modified release formulations offer a steady release of drug into circulation. Several authors have also investigated the complex interactions between swelling, erosion and diffusion kinetics for drug release for these natural polymers (Nokhodchi et al, 2015;Nokhodchi and Asare-Addo, 2014;Nokhodchi, Raja, Patel, & Asare-Addo, 2012;Crowley et al, 2004;Naggar et al, 1992;Bonferoni et al, 1993;Sujja-areevath et al, 1996;Talukdar et al, 1996;Khullar et al, 1998;Kaialy et al, 2013;Nep et al, 2015Nep et al, , 2017Siahi-Shadbad et al, 2011;Peppas and Sahlin, 1989;Lee and Kim, 1991;Colombo et al, 1995;Reynolds et al, 1998). These renewable sources of natural polymers have greater advantages over their synthetic and semisynthetic counterparts in the developing world (Nep et al, 2016a).…”
mentioning
confidence: 99%
“…Moreover, the swelling effect on NaCMC is restricted by the organized structure of cellulose and also by a high T g (~121 °C) [ 44 ]. Cellulose chains form intra and inter-molecular bonds, which results in an organized chain structure with a high crystallinity [ 21 ].…”
Section: Resultsmentioning
confidence: 99%