Introduction: Hyperprotein dietary interventions, especially in obese and overweight people, favor a great loss of body fat and still preserve lean mass. General Objective: to elucidate the mechanism of action of high-protein diets in reducing body fat. Methodology: To carry out this study, we opted for research in the form of an integrative literature review. The integrative review determines current knowledge on a specific topic, as it is conducted in order to identify, analyze and synthesize results of independent studies on the same subject. Results and Discussion: To carry out this study we opted for a research in the modality of integrative literature review. The integrative review determines current knowledge on a specific topic, as it is conducted in order to identify, analyze and synthesize results of independent studies on the same subject. Conclusion: Through the development of this study, it was possible to demonstrate through the literature, the benefits of a high-protein diet, its help in reducing fat and body weight.