2022
DOI: 10.1101/2022.12.03.518961
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Application of self-organizing maps to AFM-based viscoelastic characterization of breast cancer cell mechanics

Abstract: Cell mechanical properties have been proposed as label free markers for diagnostic purposes in diseases such as cancer. Cancer cells show altered mechanical phenotypes compared to their healthy counterparts. Atomic Force Microscopy (AFM) is a widely utilized tool to study cell mechanics. These measurements often need skilful users, physical modelling of mechanical properties and expertise in data interpretation. Together with the need to perform many measurements for statistical significance and to probe wide … Show more

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