Application of surfactant assisted dispersive liquid–liquid microextraction as an efficient sample treatment technique for preconcentration and trace detection of zonisamide and carbamazepine in urine and plasma samples

Behbahani, Mohammad; Najafi, Fatemeh; Bagheri, Saman; Bojdi, Majid Kalate; Salarian, Mani; Bagheri, Abbas

doi:10.1016/j.chroma.2013.07.088

Cited by 77 publications

(38 citation statements)

References 30 publications

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“…Preconcentration is a very important issue for achievement of low detection limits (Behbahani et al 2014i, j;Salarian et al 2014;Ebrahimzadeh and Behbahani 2013). Several procedures have been developed for these purposes such as liquid-liquid extraction (LLE) (Silvestre et al 2009), liquid phase microextraction (LPME) (Behbahani et al 2013bHossienpoor-Zaryabi et al 2014;Naeemullah et al 2013Naeemullah et al , 2014Unsal et al 2014) co-precipitation (Saracoglu et al 2003;Doner and Ege 2005), and solid phase extraction (SPE) (Bagheri et al 2012a, b;Nabid et al 2012Nabid et al , 2014Ghorbani-Kalhor et al 2014;Behbahani et al 2015;Omidi et al 2014a, b). However, some of these pretreatment methods need large amounts of sample and/or organic solvents, are time-consuming and expensive, and have unsatisfactory enrichment factors.…”

Section: Introductionmentioning

confidence: 97%

Trace monitoring of silver ions in food and water samples by flame atomic absorption spectrophotometry after preconcentration with solvent-assisted dispersive solid phase extraction

Omidi

Behbahani

Shahtaheri

et al. 2015

Environ Monit Assess

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In this research, a new sample treatment technique termed solvent-assisted dispersive solid phase extraction (SADSPE) was developed. The new method was based on the dispersion of the sorbent into the sample to maximize the contact surface. In this approach, the dispersion of the sorbent at a very low milligram level was achieved by injecting a mixture solution of the sorbent and disperser solvent into the aqueous sample. Thereby, a cloudy solution formed. The cloudy solution resulted from the dispersion of the fine particles of the sorbent in the bulk aqueous sample. After extraction, the cloudy solution was centrifuged and the enriched analytes in the sediment phase dissolved in ethanol and determined by FAAS. Under the optimized conditions, the detection limit for silver ions was 0.8 μg L(-1). The relative standard deviations for six separate extraction experiments for determination of 5 and 200 μg L(-1) of silver ions was 3.4 and 3.1 %. The preconcentration factor was found to be 61.7. SADSPE was successfully applied for trace determination of silver ions in water and food samples.

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Section: Introductionmentioning

confidence: 97%

Trace monitoring of silver ions in food and water samples by flame atomic absorption spectrophotometry after preconcentration with solvent-assisted dispersive solid phase extraction

Omidi

Behbahani

Shahtaheri

et al. 2015

Environ Monit Assess

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“…A cloudy solution is formed [33] and the analytes in the sample is extracted into the fine droplets of extraction solvent, sedimented at the bottom of the conical test tube after centrifugation. The amount of analytes in the sedimented phase can be determined by instrumental analysis.…”

Section: Methodsmentioning

confidence: 99%

Determination of thallium in environmental samples by surfactant assisted dispersive liquid-liquid microextraction combined with first order derivative spectrophotometry

2015

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A surfactant assisted dispersive liquid-liquid microextraction (SA-DLLME) combined with derivative spectrophotometric method has been proposed for the determination of thallium(III) using a chelating agent diacetylmonoxime-p-hydroxybenzoylhydrazone. Disperser solvent was substituted by surfactant, which made the emulsification more effective and extraction, quite environment friendly. Carbon tetrachloride was employed as the extractant. The developed SA-DLLME technique was coupled with first order derivative spectrophotometric method to improve the analytical performance. Optimum conditions relevant to SA-DLLME and instrumental parameters were studied in detail. The enrichment factor of the method was found to be 23. The limit of detection and quantitation limit of first order derivative spectrophotometric method were found to be 0.22 and 0.67 µg/L, respectively. The relative standard deviation (RSD) for five replicates of 50.0 µg/L of thallium(III) was found to be 1.12%. The applicability of the method was evaluated by the trace level determination of thallium in different environmental samples.

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“…The use of chromatographic methods for pharmaceutical analysis in comparison to other analytical methods has several advantages including high versatility, selectivity and efficiency, in addition to its ability to be coupled with different sample extraction techniques [30–33]. Micellar liquid chromatography (MLC) is advantageous over conventional liquid chromatography due to several reasons including the smaller concentration of organic solvent in the mobile phase which render it cheaper and less toxic, the improved selectivity and ability to separate different hydrophobic and hydrophilic analytes due to variable mechanisms of interaction between analytes and the mobile and stationary phases, the excellent solubilizing power of micelles and the ability to use direct injection of complex sample matrices including biological fluids without pretreatment procedures [34–36].…”

Section: Introductionmentioning

confidence: 99%

Rapid micellar HPLC analysis of loratadine and its major metabolite desloratadine in nano-concentration range using monolithic column and fluorometric detection: application to pharmaceuticals and biological fluids

Belal

El-Razeq

El-Awady

et al. 2016

Chemistry Central Journal

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BackgroundLoratadine is a commonly used selective non-sedating antihistaminic drug. Desloratadine is the active metabolite of loratadine and, in addition, a potential impurity in loratadine bulk powder stated by the United States Pharmacopeia as a related substance of loratadine. Published methods for the determination of both analytes suffer from limited throughput due to the time-consuming steps and tedious extraction procedures needed for the analysis of biological samples. Therefore, there is a strong demand to develop a simple rapid and sensitive analytical method that can detect and quantitate both analytes in pharmaceutical preparations and biological fluids without prior sample extraction steps.ResultsA highly-sensitive and time-saving micellar liquid chromatographic method is developed for the simultaneous determination of loratadine and desloratadine. The proposed method is the first analytical method for the determination of this mixture using a monolithic column with a mobile phase composed of 0.15 M sodium dodecyl sulfate, 10% n-Butanol and 0.3% triethylamine in 0.02 M phosphoric acid, adjusted to pH 3.5 and pumped at a flow rate of 1.2 mL/min. The eluted analytes are monitored with fluorescence detection at 440 nm after excitation at 280 nm. The developed method is linear over the concentration range of 20.0–200.0 ng/mL for both analytes. The method detection limits are 15.0 and 13.0 ng/mL and the limits of quantification are 20.0 and 18.0 ng/mL for loratadine and desloratadine, respectively. Validation of the developed method reveals an accuracy of higher than 97% and intra- and inter-day precisions with relative standard deviations not exceeding 2%.ConclusionsThe method can be successfully applied to the determination of both analytes in various matrices including pharmaceutical preparations, human urine, plasma and breast milk samples with a run-time of less than 5 min and without prior extraction procedures. The method is ideally suited for use in quality control laboratories. Moreover, it could be a simple time-saving alternative to the official pharmacopeial method for testing desloratadine as a potential impurity in loratadine bulk powder.Graphical abstractTypical chromatogram of loratadine and its major metabolite desloratadine using the proposed micellar HPLC method

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Application of surfactant assisted dispersive liquid–liquid microextraction as an efficient sample treatment technique for preconcentration and trace detection of zonisamide and carbamazepine in urine and plasma samples

Cited by 77 publications

References 30 publications

Trace monitoring of silver ions in food and water samples by flame atomic absorption spectrophotometry after preconcentration with solvent-assisted dispersive solid phase extraction

Trace monitoring of silver ions in food and water samples by flame atomic absorption spectrophotometry after preconcentration with solvent-assisted dispersive solid phase extraction

Determination of thallium in environmental samples by surfactant assisted dispersive liquid-liquid microextraction combined with first order derivative spectrophotometry

Rapid micellar HPLC analysis of loratadine and its major metabolite desloratadine in nano-concentration range using monolithic column and fluorometric detection: application to pharmaceuticals and biological fluids

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