Application of the chicken embryo in testing for embryotoxicity: thiurams.

A study towards release dynamics of thiram fungicide from starch–alginate beads to control environmental and health hazards

“…The disulfide group present in thiram has been reported to cause cytotoxicity due to the oxidation of -SH groups of cellular proteins, peptides and cofactors [16]. Thiram is also known as an inducer of allergic contact dermatitis and skin lesions including hand eczema or dermatitis have been often recognized among exposed workers [17][18][19]. Thiram has also been reported to have adverse effects on hepatic system [20], the reproductive system [21,17,18], and on the developmental processes [19].…”

“…Thiram is also known as an inducer of allergic contact dermatitis and skin lesions including hand eczema or dermatitis have been often recognized among exposed workers [17][18][19]. Thiram has also been reported to have adverse effects on hepatic system [20], the reproductive system [21,17,18], and on the developmental processes [19]. The acute oral LD 50 value of thiram is 375 mg/kg for rats [22,23].…”

Development of a new controlled pesticide delivery system based on neem leaf powder

“…In this study, we have used thiram as a model pesticide that has been used as a fungicide to control soil fungi that cause root rot diseases of plants [24] and has been used to protect harvested crops, cereals, seeds, fruits, vegetables, and turf crops from deterioration in storage or transport [25,26]. Like other pesticides it has also been reported to have adverse effects on hepatic system [27], the reproductive system [28,29] and on the developmental processes [30]. Therefore, the present study is an attempt to synthesize NLPalginate based formulations for controlled and sustained release of thiram fungicide.…”

Embryotoxic Effects of Acrolein, Methacrylates, Guanidines and Resorcinol on Three Day Chicken Embryos

“…Until now, the results from tests with 42 chemicals are available in our laboratory (Korhonen et a/. 1982a(Korhonen et a/.…”