Application of the Ugi reaction for the preparation of enzyme electrodes

Vrbova, E.; Marek, M.

doi:10.1016/s0003-2670(00)83860-x

Cited by 19 publications

(8 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This coupling reaction was carried out in water (pH 7) at 25 C, in which high immobilization yield was achieved. Unlike the other report, 11 our investigation showed negligible immobilization of RML in sodium phosphate buffer solution even at low ionic strength (5 mM) aer 24 h of incubation.…”

Section: Covalent Immobilization Of Rmlcontrasting

confidence: 94%

“…Vrbova and Marek have claimed immobilization of trypsin on chemically modied nylons via a multi component reaction. 11 They performed coupling of the protein to the support in presence of glutaraldehyde with and without cyclohexyl isocyanide in a buffer solution. They concluded performance of multicomponent reaction only from the differences between the stability of the nal derivatives obtained by the two methods.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Rapid and high-density covalent immobilization of Rhizomucor miehei lipase using a multi component reaction: application in biodiesel production

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Covalent Immobilization Of Rmlcontrasting

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Rapid and high-density covalent immobilization of Rhizomucor miehei lipase using a multi component reaction: application in biodiesel production

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In 1990, Vrbova and Marek executed the coimmobilization of glucose oxidase and catalase on the surface of the net nylon with Ugi-4CR approach for the preparation of D -glucose biosensor . The reaction proceeded with partially hydrolyzed of nylon net 89 with a 3969 cm –1 mesh and thickness of 100 μm by HCl.…”

Section: Covalent Functionalization Through Multicomponent Reactionsmentioning

confidence: 99%

Materials Functionalization with Multicomponent Reactions: State of the Art

Afshari

Shaabani

2018

ACS Comb. Sci.

View full text Add to dashboard Cite

The emergence of neoteric synthetic routes for materials functionalization is an interesting phenomenon in materials chemistry. In particular, the union of materials chemistry with multicomponent reactions (MCRs) opens a new avenue leading to the realm of highly innovative functionalized architectures with unique features. MCRs have recently been recognized as considerable part of the synthetic chemist's toolbox due to their great efficiency, inherent molecular diversity, atom and pot economy along with operational simplicity. Also, MCRs can improve E-factor and mass intensity as important green chemistry metrics. By rational tuning of the materials, as well as the MCRs, wide ranges of functionalized materials can be produced with tailorable properties that can play important roles in the plethora of applications. To date, there has not reported any exclusive review of a materials functionalization with MCRs. This critical review highlights the state-of-the-art on the one-pot functionalization of carbonaceous and siliceous materials, polysaccharides, proteins, enzymes, synthetic polymers, etc., via diverse kind of MCRs like Ugi, Passerini, Petasis, Khabachnik-Fields, Biginelli, and MALI reactions through covalent or noncovalent manners. Besides the complementary discussion of synthetic routes, superior properties and detailed applicability of each functionalized material in modern technologies are discussed. Our outlook also emphasizes future strategies for this unprecedented area and their use as materials for industrial implementation. With no doubt, MCRs-functionalization of materials bridges the gap between materials science domain and applied chemistry.

show abstract

“…Another approach for the construction of biosensors based on the MCR strategy was developed by Vrbova and Marek, who used collagen as a natural material to fabricate an enzyme-catalyzed electrode for D-galactose determination. They immobilized galactose oxidase or co-immobilized galactose oxidase plus catalase to a Clark-type oxygen sensor using the Ugi-four component MCR ( Vrbová and Marek, 1990 ). In this approach, the prepared biosensor was investigated for the detection of D-galactose in real samples of plasma and serum from patients with suspected galactosemia.…”

Section: Routes For Improvementmentioning

confidence: 99%

Green chemistry and coronavirus

Ahmadi

Rabiee

Fatahi

et al. 2021

Sustainable Chemistry and Pharmacy

View full text Add to dashboard Cite

The novel coronavirus pandemic has rapidly spread around the world since December 2019. Various techniques have been applied in identification of SARS-CoV-2 or COVID-19 infection including computed tomography imaging, whole genome sequencing, and molecular methods such as reverse transcription polymerase chain reaction (RT-PCR). This review article discusses the diagnostic methods currently being deployed for SARS-CoV-2 identification including optical biosensors and point-of-care diagnostics that are on the horizon. These innovative technologies may provide a more accurate, sensitive and rapid diagnosis of SARS-CoV-2 to manage the present novel coronavirus outbreak, and could be beneficial in preventing any future epidemics. Furthermore, the use of green synthesized nanomaterials in the optical biosensor devices could leads to sustainable and environmentally-friendly approaches for this crisis.

show abstract

Application of the Ugi reaction for the preparation of enzyme electrodes

Cited by 19 publications

References 15 publications

Rapid and high-density covalent immobilization of Rhizomucor miehei lipase using a multi component reaction: application in biodiesel production

Rapid and high-density covalent immobilization of Rhizomucor miehei lipase using a multi component reaction: application in biodiesel production

Materials Functionalization with Multicomponent Reactions: State of the Art

Green chemistry and coronavirus

Contact Info

Product

Resources

About