ObjectivesOral health‐related behaviors in hemodialysis patients are reduced, potentially leading to adverse consequences. The aim of the present study was to evaluate dental cleaning behavior (DCB) and related factors among hemodialysis patients.MethodsThis cross‐sectional study was carried out in Sanandaj city, in the west of Iran in 2022. Using the census method, 115 hemodialysis patients from the dialysis center of Tohid Hospital were recruited. Data were gathered by a three‐section questionnaire. The first section included demographic characteristics, the second section involved variables related to the health belief model (HBM), and the third section assessed stages of DCB change based on the trans‐theoretical model. Analysis of data was done by assessing frequency, descriptive and inferential statistics such as t test, correlation coefficient, and regression.ResultsOnly 26.1% of participants reported DCB, defined as tooth brushing at least twice daily; 30.4% were in the precontemplation stage, 26.1% in contemplation, and 17.4% in the preparation stage. Perceived self‐efficacy was lower among patients who did not perform DCB. The odds of DCB increased with perceived self‐efficacy (odds ratio [OR] = 1.51, 95% confidence interval [CI] = 1.19–1.92, p < .05), cues to action (OR = 1.63, 95% CI = 1.03–2.55, p < .05), and decreased with perceived barriers (OR = 0.68, 95% CI = 0.47–0.97, p < .01).ConclusionsDCB of patients on hemodialysis requires improvement. Perceived self‐efficacy, cues to action, and perceived barriers constructs of the HBM should be considered in interventional programs targeting to increase oral health as well as in future research in the field.