Application of UPLC-Orbitrap-HRMS targeted metabolomics in screening of allelochemicals and model plants of ginseng

Meng, Xiangru; Huang, Xin; Li, Qiong; Wang, Enpeng; Chen, Changbao

doi:10.1016/j.jplph.2023.153996

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…CC ginseng soil was examined to inspect metabolomics and to verify its autotoxic activity. The effects of allelochemicals on ginseng's development were used to screen and assess 23 ginsenosides and their contributions to autotoxic effects, which inhibit plant growth [112]. The metabolite profiles of several medicinal plants were altered significantly as a result of CCO.…”

Section: Metabolomics Analysismentioning

confidence: 99%

A Systematic Review on the Continuous Cropping Obstacles and Control Strategies in Medicinal Plants

Zeeshan Ul Haq,

Yu,

Yao

et al. 2023

IJMS

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Continuous cropping (CC) is a common practice in agriculture, and usually causes serious economic losses due to soil degeneration, decreased crop yield and quality, and increased disease incidence, especially in medicinal plants. Continuous cropping obstacles (CCOs) are mainly due to changes in soil microbial communities, nutrient availability, and allelopathic effects. Recently, progressive studies have illustrated the molecular mechanisms of CCOs, and valid strategies to overcome them. Transcriptomic and metabolomics analyses revealed that identified DEGs (differently expressed genes) and metabolites involved in the response to CCOs are involved in various biological processes, including photosynthesis, carbon metabolism, secondary metabolite biosynthesis, and bioactive compounds. Soil improvement is an effective strategy to overcome this problem. Soil amendments can improve the microbial community by increasing the abundance of beneficial microorganisms, soil fertility, and nutrient availability. In this review, we sum up the recent status of the research on CCOs in medicinal plants, the combination of transcriptomic and metabolomics studies, and related control strategies, including uses of soil amendments, crop rotation, and intercropping. Finally, we propose future research trends for understanding CCOs, and strategies to overcome these obstacles and promote sustainable agriculture practices in medicinal plants.

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Section: Metabolomics Analysismentioning

confidence: 99%

A Systematic Review on the Continuous Cropping Obstacles and Control Strategies in Medicinal Plants

Zeeshan Ul Haq,

Yu,

Yao

et al. 2023

IJMS

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“…Ginsenoside Rg 1 induces the cell apoptosis of notoginseng root by the excessive accumulation of reactive oxygen species (ROS) [11]. The ginsenosides extracted from continuously cropped problem soil have an impact on the germination and growth of ginseng seedlings via significant changes in indicators such as superoxide dismutase (SOD) [12]. Ginsenosides Rg 1 , Rb 1 , Rh 1 , and their mixtures could disrupt the balance of fungal microbiota by stimulating potential soil-borne pathogens [13,14].…”

Section: Introductionmentioning

confidence: 99%

Analysis Transcriptome and Phytohormone Changes Associated with the Allelopathic Effects of Ginseng Hairy Roots Induced by Different-Polarity Ginsenoside Components

Zhou,

Li,

Huang

et al. 2024

Molecules

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The allelopathic autotoxicity of ginsenosides is an important cause of continuous cropping obstacles in ginseng planting. There is no report on the potential molecular mechanism of the correlation between polarity of ginsenoside components and their allelopathic autotoxicity. This study applied a combination of metabolomics and transcriptomics analysis techniques, combined with apparent morphology, physiological indexes, and cell vitality detection of the ginseng hairy roots, through which the molecular mechanism of correlation between polarity and allelopathic autotoxicity of ginsenosides were comprehensively studied. The hairy roots of ginseng presented more severe cell apoptosis under the stress of low-polarity ginsenoside components (ZG70). ZG70 exerted allelopathic autotoxicity by regulating the key enzyme genes of cis-zeatin (cZ) synthesis pathway, indole-3-acetic acid (IAA) synthesis pathway, and jasmonates (JAs) signaling transduction pathway. The common pathway for high-polarity ginsenoside components (ZG50) and ZG70 to induce the development of allelopathic autotoxicity was through the expression of key enzymes in the gibberellin (GA) signal transduction pathway, thereby inhibiting the growth of ginseng hairy roots. cZ, indole-3-acetamid (IAM), gibberellin A1 (GA1), and jasmonoyl-L-isoleucine (JA-ILE) were the key response factors in this process. It could be concluded that the polarity of ginsenoside components were negatively correlated with their allelopathic autotoxicity.

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Recent advancement in mass based plant metabolomics: techniques, tools, and analytical approaches

Kumar,

Bharat,

Kumar

et al. 2024

Phytochem Rev

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Application of UPLC-Orbitrap-HRMS targeted metabolomics in screening of allelochemicals and model plants of ginseng

Cited by 5 publications

References 28 publications

A Systematic Review on the Continuous Cropping Obstacles and Control Strategies in Medicinal Plants

A Systematic Review on the Continuous Cropping Obstacles and Control Strategies in Medicinal Plants

Analysis Transcriptome and Phytohormone Changes Associated with the Allelopathic Effects of Ginseng Hairy Roots Induced by Different-Polarity Ginsenoside Components

Recent advancement in mass based plant metabolomics: techniques, tools, and analytical approaches

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